Can aminopeptidase N determined in the meconium be a candidate for biomarker of fetal intrauterine environment?
Sign Up to like & getrecommendations! Published in 2020 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2020.104446
Abstract: AIM To investigate possible association of aminopeptidase N/CD13 with other parameters of possible homeostatic mechanisms in meconium for potential use in identifying intrauterine environmental stress factors during fetal and perinatal life. METHODS Aminopeptidase N/CD13 (APN/CD13),… read more here.
Keywords: aminopeptidase; apn cd13; candidate biomarker; cer ... See more keywords
Quantitative profiling of CD13 on single acute myeloid leukemia cells by super-resolution imaging and its implication in targeted drug susceptibility assessment.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c8nr06526h
Abstract: Quantitative profiling of membrane proteins on the cell surface is of great interest in tumor targeted therapy and single cell biology. However, the existing technologies are either of insufficient resolution, or unable to provide precise… read more here.
Keywords: quantitative profiling; resolution; microscopy; cell surface ... See more keywords
CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration
Sign Up to like & getrecommendations! Published in 2019 at "Science Signaling"
DOI: 10.1126/scisignal.aav5938
Abstract: The cell surface peptidase CD13 coordinates β1 integrin recycling to promote cell migration. Recycle and go forth! Cell migration and motility are critical to embryonic development, immunity, and tissue repair, but uncontrolled migration can lead… read more here.
Keywords: cell migration; surface; integrin recycling; migration ... See more keywords
The Role of the Ectopeptidase APN/CD13 in Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11030724
Abstract: APN/CD13 is expressed in a variety of cells/tissues and is therefore associated with diverse physiological functions, including proliferation, differentiation, migration, angiogenesis, invasion, metastasis, vasoconstriction, and the regulation of normal and impaired immune function. Increased expression… read more here.
Keywords: cd13; ectopeptidase apn; cd13 cancer; role ectopeptidase ... See more keywords
Therapeutic Performance Evaluation of 213Bi-Labelled Aminopeptidase N (APN/CD13)-Affine NGR-Motif ([213Bi]Bi-DOTAGA-cKNGRE) in Experimental Tumour Model: A Treasured Tailor for Oncology
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020491
Abstract: Since NGR-tripeptides (asparagine-glycine-arginine) selectively target neoangiogenesis-associated Aminopeptidase N (APN/CD13) on cancer cells, we aimed to evaluate the in vivo tumour targeting capability of radiolabelled, NGR-containing, ANP/CD13-selective [213Bi]Bi-DOTAGA-cKNGRE in CD13pos. HT1080 fibrosarcoma-bearing severe combined immunodeficient CB17… read more here.
Keywords: 213bi dotaga; oncology; dotaga ckngre; cd13 ... See more keywords