The Interaction between DNMT1 and High‐Mannose CD133 Maintains the Slow‐Cycling State and Tumorigenic Potential of Glioma Stem Cell
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202216
Abstract: The quiescent/slow‐cycling state preserves the self‐renewal capacity of cancer stem cells (CSCs) and leads to the therapy resistance of CSCs. The mechanisms maintaining CSCs quiescence remain largely unknown. Here, it is demonstrated that lower expression… read more here.
Keywords: interaction; cd133; slow cycling; cycling state ... See more keywords
CD133: An emerging prognostic factor and therapeutic target in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11243
Abstract: Colorectal cancer (CRC) is one of the leading causes of death worldwide. Recently, the role of cancer stem cells (CSCs) has been highlighted as a crucial emerging factor in chemoresistance, cancer relapse, and metastasis. CD133… read more here.
Keywords: cd133; colorectal cancer; emerging prognostic; cd133 emerging ... See more keywords
CD133 suppression increases the sensitivity of prostate cancer cells to paclitaxel
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05411-9
Abstract: One of the major barriers in cancer therapy is the resistance to conventional therapies and cancer stem cells (CSCs) are among the main causes of this problem. CD133 as a CSC marker displays stem cell-like… read more here.
Keywords: cd133 sirna; cd133; prostate cancer; cancer ... See more keywords
Endothelial Progenitor Cell CD34+ and CD133+ Concentrations and Soluble HLA-G Concentrations During Pregnancy and in Cord Blood in Undifferentiated Connective Tissue Diseases Compared to Controls
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DOI: 10.1007/s43032-020-00405-1
Abstract: The objective of this study is to evaluate endothelial progenitor cells (EPCs) CD34+ CD133− and CD34+ CD133+ and soluble HLA-G (sHLA-G) concentrations among undifferentiated connective tissue disease (UCTD) subjects, compared to controls, during pregnancy and… read more here.
Keywords: cd133; cd34 cd133; cord blood;
Hypomyelination and cognitive impairment in mice lacking CD133 (Prominin-1).
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.05.072
Abstract: The CD133 antigen, also known as prominin-1, is a glycoprotein that specifically localizes to plasma membrane protrusions. The precise function of CD133 remains unknown, but it is expressed in various progenitor cells including those derived… read more here.
Keywords: lacking cd133; hypomyelination; cd133; prominin ... See more keywords
Analysis of the COMPARE-AMI trial: First report of long-term safety of CD133+ cells.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2020.06.004
Abstract: BACKGROUND Data related to long-term safety of intracoronary (IC) injection of CD133+ bone marrow stem cells (BMSC) following an acute myocardial infarction (MI) are still lacking. METHODS COMPARE-AMI is a double-blind, placebo-controlled phase II clinical… read more here.
Keywords: cd133; term safety; trial; long term ... See more keywords
Association Between CD133, CD44, and Nestin Expression and Prognostic Factors in High-Grade Meningioma.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.12.067
Abstract: BACKGROUND Meningioma is the most common primary brain tumor. It is graded as I, II, or III based on the World Health Organization (WHO) classification of central nervous system tumors. Meningiomas, especially those classified as… read more here.
Keywords: grade; nestin expression; cd133; cd44 ... See more keywords
The Effect of Resveratrol and Quercetin on Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem Cell
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DOI: 10.1080/01635581.2019.1670853
Abstract: Abstract Resveratrol and quercetin are phytochemicals that are found in a variety of plants. The aim of this study was to investigate the effect of resveratrol and quercetin on epithelial-mesenchymal transition (EMT) of CD133+ and… read more here.
Keywords: resveratrol; cd133; pancreatic cancer; resveratrol quercetin ... See more keywords
Transforming growth factor-β makes the key characteristics of the proteome CD133- differentiated cells closer to CD133+ cancer stem cells of glioblastoma
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DOI: 10.1093/annonc/mdz447.024
Abstract: Abstract Background Invasive growth of glioblastoma multiforme (GBM) is associated with CD133 + cancer stem cells (CSCs) and differentiated CD133- glioblastoma cells (DGCs) formed under the influence of transforming growth factor (TGF-β). The aim of… read more here.
Keywords: cd133; growth; cd133 cancer; stem cells ... See more keywords
MicroRNA-135a-induced formation of CD133+ subpopulation with cancer stem cell properties in cervical cancer.
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DOI: 10.1093/carcin/bgaa025
Abstract: Cancer stem cells (CSCs) play significant roles in tumor initiation. MicroRNA-135a (miR-135a) induced the formation of a CD133+ subpopulation from a human papillomavirus-immortalized cervical epithelial cell line. Compared with the CD133- cells, the CD133+ cells… read more here.
Keywords: cd133; 135a induced; formation; subpopulation ... See more keywords
Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells"
DOI: 10.1093/stmcls/sxac007
Abstract: CD133 is a transmembrane protein that mainly localizes to the plasma membrane in hematopoietic/neural stem cells and cancer stem cells. Although CD133 also localizes to the cytoplasm and is degraded through autophagy, the precise mechanisms… read more here.
Keywords: autophagic activity; cd133 endosomes; cd133; pericentrosomal cd133 ... See more keywords