Synergistic role of circulating CD14++CD16+ monocytes and fibrinogen in predicting the cardiovascular events after myocardial infarction
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Cardiology"
DOI: 10.1002/clc.24005
Abstract: Monocytes and fibrinogen (FIB) play important roles in driving acute and reparative inflammatory pathways after myocardial infarction (MI). In humans, there are three subsets of monocytes, namely, CD14++CD16− (Mon1), CD14++CD16+ (Mon2), and CD14+CD16++ (Mon3). During… read more here.
Keywords: cd14 cd16; cd16; monocytes fibrinogen; myocardial infarction ... See more keywords
Frontline Science: Buprenorphine decreases CCL2‐mediated migration of CD14+CD16+ monocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3hi0118-015r
Abstract: HIV infection of the CNS causes neuroinflammation and damage that contributes to the development of HIV‐associated neurocognitive disorders (HAND) in greater than 50% of HIV‐infected individuals, despite antiretroviral therapy (ART). Opioid abuse is a major… read more here.
Keywords: hiv; cd16 monocytes; cd14 cd16; ccl2 mediated ... See more keywords
Altered Monocyte Subsets in Patients with Chronic Idiopathic Neutropenia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-019-00694-5
Abstract: To the editor, Chronic idiopathic neutropenia (CIN) of adults is a neutrophil disorder characterized by the persistent and unexplained reduction in the number of peripheral blood (PB) neutrophils below the lower limit of the normal… read more here.
Keywords: cin; cd16; cd14 cd16; chronic idiopathic ... See more keywords
Characteristics of circulating monocytes at baseline and after activation in patients with intracranial aneurysm.
Sign Up to like & getrecommendations! Published in 2019 at "Human immunology"
DOI: 10.1016/j.humimm.2019.11.003
Abstract: Intracranial aneurysm (IA) is a bulging of blood vessels around the brain that is often asymptomatic but may cause severe complications and death if ruptured. Macrophage-mediated immune responses can contribute to the development of IA.… read more here.
Keywords: intracranial aneurysm; circulating monocytes; cd14 cd16; expression ... See more keywords
Expression of CD206 and CD163 on intermediate CD14++CD16+ monocytes are increased in hemorrhagic fever with renal syndrome and are correlated with disease severity.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.05.021
Abstract: BACKGROUND Hantaan virus infection causes lethal hemorrhagic fever with renal syndrome (HFRS) in humans. Little is known about how monocytes contribute to HFRS pathogenesis. In this study, we aimed to investigate changes in various monocyte… read more here.
Keywords: cd206; cd16; cd16 monocytes; cd163 ... See more keywords
Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.01.002
Abstract: AIMS Mouse studies have established distinct monocyte subtypes that participate in the process of atherosclerotic lesion formation. The pro-inflammatory Ly6Chigh monocyte subtype actively contributes to murine plaque progression and destabilization. Also in humans, different peripheral… read more here.
Keywords: vulnerable plaque; cd16 classical; monocytes associate; cd14 cd16 ... See more keywords
Inflammation linked to Takotsubo
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-018-0128-3
Abstract: acute stress-induced (Takotsubo) cardiomyopathy is typically associated with a major stressful event and has a similar presentation to that of acute myocardial infarction, but its precise pathogenesis is unclear. a new study shows that this… read more here.
Keywords: infiltration myocardium; patients acute; inflammation; takotsubo ... See more keywords
Characterization of human peritoneal monocyte/macrophage subsets in homeostasis: Phenotype, GATA6, phagocytic/oxidative activities and cytokines expression
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-30787-x
Abstract: Peritoneal macrophages play a critical role in the control of infectious and inflammatory diseases. Although recent progress on murine peritoneal macrophages has revealed multiple aspects on their origin and mechanisms involved in their maintenance in… read more here.
Keywords: human peritoneal; peritoneal macrophages; cd14 cd16; expression ... See more keywords
Contribution of the uremic milieu to an increased pro-inflammatory monocytic phenotype in chronic kidney disease
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46724-5
Abstract: Intermediate (CD14++CD16+) monocytes have important pro-inflammatory and atherogenic features and are increased in patients with chronic kidney disease (CKD). The present study aims to elucidate the role of the uremic milieu and of platelet activation… read more here.
Keywords: cd16 monocytes; cd14 cd16; pro inflammatory; uremic milieu ... See more keywords
Monocyte Heterogeneity in Cardiovascular Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Cardiovascular research"
DOI: 10.1093/cvr/cvad069
Abstract: Monocytes circulate the vasculature at steady state and are recruited to sites of inflammation where they differentiate into macrophages (MФ) to replenish tissue-resident MФ populations and engage in the development of cardiovascular disease (CVD). Monocytes… read more here.
Keywords: cardiovascular disease; heterogeneity; monocyte heterogeneity; cd14 cd16 ... See more keywords
Prognostic value of Toll-like receptor 4 on human monocyte subsets combined with computed tomography-adapted Leaman score assessing coronary artery disease.
Sign Up to like & getrecommendations! Published in 2023 at "Coronary artery disease"
DOI: 10.1097/mca.0000000000001250
Abstract: BACKGROUND Upregulation of Toll-like receptor 4 (TLR-4) is associated with coronary plaque vulnerability assessed by coronary computed tomography angiography (CCTA). Computed tomography-adapted Leaman score (CT-LeSc) is an independent long-term predictor of cardiac events. The relationship… read more here.
Keywords: cd14 cd16; cd14; cardiac events; expression ... See more keywords