Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250019
Abstract: Nowadays laparoscopic interventions enable the collection of resident macrophage populations out of the human cavities. We employed this technique to isolate pleural monocytes/macrophages from healthy young adults who underwent a correction of pectus excavatum. High… read more here.
Keywords: macrophages healthy; cd14 monocytes; monocytes macrophages; high expression ... See more keywords
CCL15 Recruits Suppressive Monocytes to Facilitate Immune Escape and Disease Progression in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30134
Abstract: Chemokines play a key role in orchestrating the recruitment and positioning of myeloid cells within the tumor microenvironment. However, the tropism regulation and functions of these cells in hepatocellular carcinoma (HCC) are not completely understood.… read more here.
Keywords: hepatocellular carcinoma; hcc; ccr1; cd14 monocytes ... See more keywords
A high number of PD-L1+ CD14+ monocytes in peripheral blood is correlated with shorter survival in patients receiving immune checkpoint inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02686-6
Abstract: Targeting of anti-programmed cell death protein-1 (PD-1) and anti-programmed death-ligand 1 (PD-L1) is a standard therapeutic strategy for various cancers. The aim of the present study was to investigate the prognostic effect of pretreatment PD-L1… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; peripheral blood; cancer ... See more keywords
Imbalance Between Soluble and Membrane-Bound CD100 Regulates Monocytes Activity in Hepatitis B Virus-Associated Acute-on-Chronic Liver Failure.
Sign Up to like & getrecommendations! Published in 2021 at "Viral immunology"
DOI: 10.1089/vim.2020.0311
Abstract: CD100 is an important immune semaphorin that is a secreted and membrane bound protein involved in infectious diseases. However, CD100 expression profile and the regulation to innate immune system in hepatitis B virus (HBV)-associated acute-on-chronic… read more here.
Keywords: aclf patients; membrane bound; hbv aclf; cd100 ... See more keywords
Increased Interleukin-35 suppresses peripheral CD14+ monocytes function in patients with Kawasaki disease
Sign Up to like & getrecommendations! Published in 2020 at "BMC Immunology"
DOI: 10.1186/s12865-020-00348-x
Abstract: Interleukin-35 (IL-35) is a newly identified IL-12 cytokine family member, which regulates the activity of immune cells in infectious diseases and autoimmune disorders. However, the regulatory function of IL-35 in Kawasaki disease is not well… read more here.
Keywords: kawasaki disease; cd14; patients kawasaki; cell ... See more keywords
RFX1 downregulation contributes to TLR4 overexpression in CD14+ monocytes via epigenetic mechanisms in coronary artery disease
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Epigenetics"
DOI: 10.1186/s13148-019-0646-9
Abstract: BackgroundToll-like receptor 4 (TLR4) expression is increased in activated monocytes, which play a critical role in the pathogenesis of coronary artery disease (CAD). However, the mechanism remains unclear. Regulatory factor X1 (RFX1) is a critical… read more here.
Keywords: overexpression; rfx1; expression; tlr4 ... See more keywords
Monocytes isolated by positive and negative magnetic sorting techniques show different molecular characteristics and immunophenotypic behaviour
Sign Up to like & getrecommendations! Published in 2017 at "F1000Research"
DOI: 10.12688/f1000research.12802.3
Abstract: Background: Magnetic sorting of cells, based on microbead conjugated antibodies (Abs), employs positive as well as negative immunomagnetic separation methods, for isolation of a specific cell population. These microbeads are suggested to be nontoxic, biodegradable… read more here.
Keywords: monocytes isolated; selection; magnetic sorting; isolated positive ... See more keywords
Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.642891
Abstract: Background Systemic sclerosis (SSc) is an autoimmune disease characterized by overproduction of extracellular matrix (ECM) and multiorgan fibrosis. Animal studies pointed to bone marrow-derived cells as a potential source of pathological ECM-producing cells in immunofibrotic… read more here.
Keywords: fibronectin levels; ssc patients; monocytes cd14; systemic sclerosis ... See more keywords
Transcription Factor MafB Suppresses Type I Interferon Production by CD14+ Monocytes in Patients With Chronic Hepatitis C
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.01814
Abstract: Transcription factor MafB regulates differentiation and activity of monocytes/macrophage and is associated with the development of atherosclerosis and cancers. However, the role of MafB in modulation of CD14+ monocytes in chronic viral hepatitis was not… read more here.
Keywords: mafb; ifn; cd14 monocytes; chronic hepatitis ... See more keywords
Upregulation of miR-941 in Circulating CD14+ Monocytes Enhances Osteoclast Activation via WNT16 Inhibition in Patients with Psoriatic Arthritis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21124301
Abstract: Psoriatic arthritis (PsA) is a destructive joint disease mediated by osteoclasts. MicroRNAs (miRNAs) regulate several important pathways in osteoclastogenesis. We profiled the expression of miRNAs in CD14+ monocytes from PsA patients and investigated how candidate… read more here.
Keywords: psoriatic arthritis; mir 941; psa patients; monocytes psa ... See more keywords