Novel gene-encoded intermolecular FRET sensor for tracking glycosylation of CD147 in living cells
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03256-0
Abstract: CD147 is involved in various physiological processes and plays important roles for tumor metastasis. Glycosylation of the protein determines numerous functions of CD147. Up to now, hardly any sensor has been developed for detecting glycosylation… read more here.
Keywords: cd147; glycosylation cd147; glycosylation; gene encoded ... See more keywords
CD147 expression lacks prognostic relevance in esophageal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-022-03917-2
Abstract: The role of CD147 as an important indicator of tumor prognosis remains controversially discussed in literature. We focused on the prognostic significance of CD147 expression in esophageal cancer patients. While some studies report that CD147… read more here.
Keywords: cancer; cd147 expression; esophageal cancer; cd147 ... See more keywords
The clinical relevance of plasma CD147/basigin in biopsy-proven kidney diseases
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-017-1518-2
Abstract: BackgroundPrecise understanding of kidney disease activity is needed to design therapeutic strategies. CD147/basigin is involved in the pathogenesis of acute kidney injury and renal fibrosis through inflammatory cell infiltration. The present study examined the clinical… read more here.
Keywords: biopsy; kidney diseases; cd147; plasma cd147 ... See more keywords
CD147 as an apoptosis regulator in spermatogenesis: deciphering its association with matrix metalloproteinases’ pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4568-y
Abstract: CD147 plays an important role in germ cells migration and survival/apoptosis during the spermatogenesis process. However, to best of our knowledge, there is no report on the exact role of CD147 gene in the regulation… read more here.
Keywords: apoptosis; cd147; cd147 gene; germ cells ... See more keywords
Resveratrol Abrogates Hypoxia-Induced Up-Regulation of Exosomal Amyloid-β Partially by Inhibiting CD147
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02742-3
Abstract: Hypoxia promotes both total extracellular and exosomal amyloid-β (Aβ) production and aggravates Alzheimer’s disease (AD). Resveratrol (RSV) has been proved to be neuroprotective in AD models, and down-regulated the expression of CD147, an additional subunit… read more here.
Keywords: induced regulation; cd147; expression; hypoxia induced ... See more keywords
Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.164
Abstract: Nonalcoholic fatty liver disease (NAFLD) represents a global health problem. Impaired autophagy has been implicated in the pathogenesis of NAFLD, and CD147 is recognized to regulate lipid metabolism in a variety of cell types. This… read more here.
Keywords: cd147; nafld mice; high fat; steatosis ... See more keywords
Differential Expression of Monocarboxylate Transporter 1 and Ancillary Protein CD147 in Red Blood Cells of Show Jumping Horses.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of equine veterinary science"
DOI: 10.1016/j.jevs.2019.102791
Abstract: We compare the expression levels of the lactate transporter complex consisting of the lactate transporter, monocarboxylate transporter 1 (MCT1), and its ancillary protein, cluster of differentiation 147 (CD147), in the membranes of red blood cells… read more here.
Keywords: cd147; lactate; jumping horses; mct1 cd147 ... See more keywords
Molecular Insights into the Interaction between CD147 and the SARS-CoV‑2 Spike Protein
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c03562
Abstract: Cluster of differentiation 147 (CD147), a transmembrane glycoprotein, has been identified as a potential auxiliary receptor for the SARS-CoV-2 spike protein (SP), contributing to COVID-19 infection. However, the detailed binding characteristics of this interaction remain… read more here.
Keywords: sars cov; spike protein; cd147; cov spike ... See more keywords
The phosphorylation of CD147 by Fyn plays a critical role for melanoma cells growth and metastasis
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-1287-3
Abstract: CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that is highly expressed in tumor cells, particularly melanoma cells, and plays critical roles in tumor cell metastasis through the regulation of… read more here.
Keywords: melanoma; phosphorylation cd147; cd147; cd147 fyn ... See more keywords
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-98266-8
Abstract: The malignant progression of colorectal cancer (CRC) is intimately associated with the abnormal regulation of transmembrane glycoprotein CD147. However, the molecular mechanism via the Rap1/Rap1GAP signaling axis has not been elucidated. This study, through integrated… read more here.
Keywords: colorectal cancer; cd147; proliferation; expression ... See more keywords
The potential mechanism of HIF-1α and CD147 in the development of triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000038434
Abstract: Background: Triple-negative breast cancer (TNBC) is a subtype of breast cancer with a poor prognosis, and the outcomes of common therapy were not favorable. Methods: The samples of 84 patients with TNBC and 40 patients… read more here.
Keywords: expression; breast cancer; hif; cd147 ... See more keywords