Synergistic role of circulating CD14++CD16+ monocytes and fibrinogen in predicting the cardiovascular events after myocardial infarction
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Cardiology"
DOI: 10.1002/clc.24005
Abstract: Monocytes and fibrinogen (FIB) play important roles in driving acute and reparative inflammatory pathways after myocardial infarction (MI). In humans, there are three subsets of monocytes, namely, CD14++CD16− (Mon1), CD14++CD16+ (Mon2), and CD14+CD16++ (Mon3). During… read more here.
Keywords: cd14 cd16; cd16; monocytes fibrinogen; myocardial infarction ... See more keywords
Glycan recognition by human blood mononuclear cells with an emphasis on dendritic cells
Sign Up to like & getrecommendations! Published in 2017 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-017-9811-6
Abstract: Dendritic cells (DCs) play crucial roles in innate and adaptive immune response, for which reason targeting antigen to these cells is an important strategy for improvement of vaccine development. To this end, we explored recognition… read more here.
Keywords: blood mononuclear; cd16 cd83; cd16; recognition ... See more keywords
Altered Monocyte Subsets in Patients with Chronic Idiopathic Neutropenia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-019-00694-5
Abstract: To the editor, Chronic idiopathic neutropenia (CIN) of adults is a neutrophil disorder characterized by the persistent and unexplained reduction in the number of peripheral blood (PB) neutrophils below the lower limit of the normal… read more here.
Keywords: cin; cd16; cd14 cd16; chronic idiopathic ... See more keywords
Expression of CD206 and CD163 on intermediate CD14++CD16+ monocytes are increased in hemorrhagic fever with renal syndrome and are correlated with disease severity.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.05.021
Abstract: BACKGROUND Hantaan virus infection causes lethal hemorrhagic fever with renal syndrome (HFRS) in humans. Little is known about how monocytes contribute to HFRS pathogenesis. In this study, we aimed to investigate changes in various monocyte… read more here.
Keywords: cd206; cd16; cd16 monocytes; cd163 ... See more keywords
Incorporation of a Novel CD16-Specific Single-Domain Antibody into Multispecific Natural Killer Cell Engagers With Potent ADCC.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00208
Abstract: Multispecific antibodies that bridge immune effector and tumor cells have shown promising preclinical and clinical efficacies. Here, we isolated and characterized novel llama single-domain antibodies (sdAbs) against CD16. One sdAb, NRC-sdAb048, bound recombinant human and… read more here.
Keywords: incorporation novel; single domain; cd16; anti cd16 ... See more keywords
Reduction in CD16/CD56 and CD16/CD3/CD56 Natural Killer Cells in Coronary Artery Disease
Sign Up to like & getrecommendations! Published in 2017 at "Immunological Investigations"
DOI: 10.1080/08820139.2017.1306866
Abstract: ABSTRACT Background: Natural killer (NK) cells are the potential modulators of inflammatory reactions that exert several unique biological effects and could lead to future adverse events of coronary artery disease (CAD). Hypothesis: The purpose of… read more here.
Keywords: reduction; cd16 cd56; natural killer; cd16 ... See more keywords
Increased Peripheral NKG2A-NKG2D+CD3-CD16+CD56dim NK Cell Subset Was Positively Correlated with Antiphospholipid Antibodies in Patients of Obstetric Antiphospholipid Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Immunological investigations"
DOI: 10.1080/08820139.2020.1835949
Abstract: Obstetric antiphospholipid syndrome (OAPS) is an autoimmune disorder with severe life-threatening complications shown during pregnancy. It has been reported that the increase in CD16+CD56dim natural killer (NK) cells in peripheral blood are risk factors for… read more here.
Keywords: nkg2a nkg2d; cd16; cd16 cd56dim; subset ... See more keywords
CD14+CD16+ monocytes are involved in daratumumab‐mediated myeloma cells killing and in anti‐CD47 therapeutic strategy
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Haematology"
DOI: 10.1111/bjh.16548
Abstract: A deep elucidation of the mechanisms of action of anti‐CD38 monoclonal antibodies (mAbs), such as daratumumab (DARA), is required to identify patients with multiple myeloma (MM) who are more responsive to this treatment. In the… read more here.
Keywords: cells killing; cd16; cd16 monocytes; cd14 cd16 ... See more keywords
FRI0291 Characterisation of monocyte populations in peripheral blood of sle patients
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.3002
Abstract: Background Systemic lupus erythematosus (SLE) is an autoimmune diseases characterised by dysregulation of immune cell function with numerous clinical manifestations. Along with B and T cells, myeloid cells play an important role in disease pathogenesis.… read more here.
Keywords: sle; cd16; sle patients; peripheral blood ... See more keywords
SAT0064 EXPANSION OF CD16+ MONOCYTE SUBSETS AND ACE EXPRESSION ARE ASSOCIATED WITH ARTERIAL THICKENING AND VASCULAR FUNCTION IN VERY EARLY RHEUMATOID ARTHRITIS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2641
Abstract: Background monocytes are largely recognized as drivers of the atherosclerosis development, the leading determinant of cardiovascular (CV) morbidity in rheumatoid arthritis (RA). Far from being a unique population, functionally and phenotypically subpopulations can be distinguished,… read more here.
Keywords: ace expression; monocyte subsets; cd16; expression associated ... See more keywords
BS30 Outlining the human monocyte inflammatory cytokine response to dietary fat intake
Sign Up to like & getrecommendations! Published in 2019 at "Heart"
DOI: 10.1136/heartjnl-2019-bcs.193
Abstract: Introduction Dysregulated immune homeostasis is implicated in atherosclerosis. Monocytes are described as inert innate immune cells that respond to vascular and inflammatory cues to extravasate into the intima then differentiate into ’active’ macrophage foam cells… read more here.
Keywords: inflammatory; expression; cytokine; response ... See more keywords