Frontline Science: Buprenorphine decreases CCL2‐mediated migration of CD14+CD16+ monocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3hi0118-015r
Abstract: HIV infection of the CNS causes neuroinflammation and damage that contributes to the development of HIV‐associated neurocognitive disorders (HAND) in greater than 50% of HIV‐infected individuals, despite antiretroviral therapy (ART). Opioid abuse is a major… read more here.
Keywords: hiv; cd16 monocytes; cd14 cd16; ccl2 mediated ... See more keywords
Expression of CD206 and CD163 on intermediate CD14++CD16+ monocytes are increased in hemorrhagic fever with renal syndrome and are correlated with disease severity.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.05.021
Abstract: BACKGROUND Hantaan virus infection causes lethal hemorrhagic fever with renal syndrome (HFRS) in humans. Little is known about how monocytes contribute to HFRS pathogenesis. In this study, we aimed to investigate changes in various monocyte… read more here.
Keywords: cd206; cd16; cd16 monocytes; cd163 ... See more keywords
Contribution of the uremic milieu to an increased pro-inflammatory monocytic phenotype in chronic kidney disease
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46724-5
Abstract: Intermediate (CD14++CD16+) monocytes have important pro-inflammatory and atherogenic features and are increased in patients with chronic kidney disease (CKD). The present study aims to elucidate the role of the uremic milieu and of platelet activation… read more here.
Keywords: cd16 monocytes; cd14 cd16; pro inflammatory; uremic milieu ... See more keywords
HIV-infected cannabis users have lower circulating CD16+ monocytes and IFN-&ggr;-inducible protein 10 levels compared with nonusing HIV patients
Sign Up to like & getrecommendations! Published in 2018 at "AIDS"
DOI: 10.1097/qad.0000000000001704
Abstract: Objective: Chronic immune activation and elevated numbers of circulating activated monocytes (CD16+) are implicated in HIV-associated neuroinflammation. The objective was to compare the level of circulating CD16+ monocytes and IFN-&ggr;-inducible protein 10 (IP-10) between HIV-infected… read more here.
Keywords: hiv donors; hiv; hiv hiv; cd16 monocytes ... See more keywords
Pretransplant Numbers of CD16+ Monocytes as a Novel Biomarker to Predict Acute Rejection After Kidney Transplantation: A Pilot Study
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Transplantation"
DOI: 10.1111/ajt.14280
Abstract: Acute rejection is one of the major immunological determinants of kidney graft function and survival. Early biomarkers to predict rejection are lacking. Emerging evidence reveals a crucial role for the monocyte/macrophage lineage cells in the… read more here.
Keywords: pretransplant numbers; acute rejection; rejection; cd16 monocytes ... See more keywords
CD14+CD16+ monocytes are involved in daratumumab‐mediated myeloma cells killing and in anti‐CD47 therapeutic strategy
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Haematology"
DOI: 10.1111/bjh.16548
Abstract: A deep elucidation of the mechanisms of action of anti‐CD38 monoclonal antibodies (mAbs), such as daratumumab (DARA), is required to identify patients with multiple myeloma (MM) who are more responsive to this treatment. In the… read more here.
Keywords: cells killing; cd16; cd16 monocytes; cd14 cd16 ... See more keywords
AB0032 DIFFERENTIAL IMPACT OF BIOLOGICS AND GLUCOCORTICOIDS ON TNF SECRETION AND CD14+CD16+ MONOCYTES PERCENTAGE IN CULTURE DERIVED FROM SYNOVIAL FLUIDS OF PATIENTS WITH PSORIATIC ARTHRITIS-IN VITRO RESEARCH
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.2064
Abstract: Inflammatory joint diseases, such as psoriatic arthritis (PsA), are frequently treated by biologics. Assessment of treatment efficacy is based upon change in clinical activity scores and in tender and swollen joint counts. Although the response… read more here.
Keywords: tnf inhibitors; cd14 cd16; tnf; cd16 monocytes ... See more keywords
Altered Monocyte Subsets in Kawasaki Disease Revealed by Single-cell RNA-Sequencing
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DOI: 10.2147/jir.s293993
Abstract: Background Kawasaki disease (KD) is characterized by a disorder of immune response, and its etiology remains unknown. Monocyte is an important member of the body’s innate immune system; however its role in KD is still… read more here.
Keywords: monocyte subsets; healthy infants; cd14 cd16; cd16 monocytes ... See more keywords
Glycolysis Is Required for LPS-Induced Activation and Adhesion of Human CD14+CD16− Monocytes
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02054
Abstract: Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are significantly elevated and migrate to the sites… read more here.
Keywords: glycolysis; cd16 monocytes; cd14 cd16; activation ... See more keywords
Activated Platelets Convert CD14+CD16- Into CD14+CD16+ Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization
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DOI: 10.3389/fimmu.2020.611133
Abstract: Monocytes are important cellular effectors of innate immune defense. Human monocytes are heterogeneous and can be classified into three distinct subsets based on CD14 and CD16 expression. The expansion of intermediate CD14+CD16+ monocytes has been… read more here.
Keywords: phagocytosis; cd16; activated platelets; cd16 monocytes ... See more keywords
CX3CL1-induced CD16+ monocytes extravasation in myeloperoxidase-ANCA-associated vasculitis correlates with renal damage
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.929244
Abstract: Background Monocytes are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Monocyte/macrophages are the dominant infiltrating cells in the glomeruli of patients with myeloperoxidase-AAV (MPO-AAV). However, how human monocyte subsets extravasate to the kidney in… read more here.
Keywords: cd16 monocytes; renal damage; aav patients; mpo aav ... See more keywords