Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.01.022
Abstract: T cells are critical effectors of cancer immunotherapies, but little is known about their gene expression programs in diffuse gliomas. Here, we leverage single-cell RNA sequencing (RNA-seq) to chart the gene expression and clonal landscape… read more here.
Keywords: cd161; single cell; analysis; cell ... See more keywords
CD161 Is Expressed in a Subset of T-Cell Prolymphocytic Leukemia Cases and Is Useful for Disease Follow-up.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqz060
Abstract: OBJECTIVES CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in… read more here.
Keywords: cd161; disease; cell prolymphocytic; prolymphocytic leukemia ... See more keywords
SAT0021 ELEVATED NUMBERS OF C-TYPE LECTIN CD161 POSITIVE PR3-SPECIFIC T-CELLS IN GPA
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6771
Abstract: Background: Various alterations of the peripheral T-cell compartment have been reported in granulomatosis with polyangiitis (GPA) such as elevated populations of CD4+CD8+ double-positive and CD4+CD161+ and CD28- single-positive effector memory T-cells (TEM) within the total… read more here.
Keywords: cd161; none declared; cd8; pr3 specific ... See more keywords
CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-003995
Abstract: Background Expression of killer cell lectin-like receptor B1 (KLRB1), the gene encoding the cell surface molecule CD161, is associated with favorable prognosis in many cancers. CD161 is expressed by several lymphocyte populations, but its role… read more here.
Keywords: cd4 cd161; cell; cd4 cells; cd4 ... See more keywords
Circulating CD3+CD4+CD161+ Cells Are Associated with Early Complications after Autologous Stem Cell Transplantation in Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/5097325
Abstract: The aim of this study was to explore if measurement of pretransplant circulating CD161-expressing cells, in addition to clinical risk factors, could predict mucositis and infections in patients with multiple myeloma (MM) undergoing autologous stem… read more here.
Keywords: cd161; cd4 cd161; cd3 cd4; early complications ... See more keywords
Clinical significance of CD161+CD4+ T cells in the development of chronic antibody-mediated rejection in kidney transplant recipients
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0200631
Abstract: In this study, we investigated whether CD161+CD4+ T cells can reflect the Th17 pathway in kidney transplant recipients (KTRs) and investigated the clinical significance of this cell type in chronic antibody-mediated rejection (cAMR) in KT.… read more here.
Keywords: cd161; cd4 cells; camr; cd161 cells ... See more keywords
Identification of CD161 expression as a novel prognostic biomarker in breast cancer correlated with immune infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.996345
Abstract: Background: CD161 has been identified as a prognostic biomarker in many neoplasms, but its role in breast cancer (BC) has not been fully explained. We aimed to investigate the molecular mechanism and prognostic value of… read more here.
Keywords: biomarker; immune infiltration; expression; cd161 ... See more keywords
A CD4+CD161+ T-Cell Subset Present in Unexposed Humans, Not Tb Patients, Are Fast Acting Cells That Inhibit the Growth of Intracellular Mycobacteria Involving CD161 Pathway, Perforin, and IFN-γ/Autophagy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.599641
Abstract: It remains undefined whether a subset of CD4+ T cells can function as fast-acting cells to control Mycobacterium tuberculosis (Mtb) infection. Here we show that the primary CD4+CD161+ T-cell subset, not CD4+CD161-, in unexposed healthy… read more here.
Keywords: cd4 cd161; cd161; growth; cd161 cell ... See more keywords
Characterization of Mucosal-Associated Invariant T Cells in Oral Lichen Planus
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021490
Abstract: Oral lichen planus (OLP) is an inflammatory condition of unknown cause that has been associated with concurrent candidal infection. Mucosal-associated invariant T (MAIT) cells express the T cell receptor TCRVα7.2 and are activated by riboflavin… read more here.
Keywords: mucosal associated; presence; mait; cd161 ... See more keywords
MCAM+CD161- Th17 Subset Expressing CD83 Enhances Tc17 Response in Psoriasis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200530
Abstract: Recent studies have highlighted the pathogenic roles of IL-17-producing CD8+ T cells (T-cytotoxic 17 [Tc17]) in psoriasis. However, the underlying mechanisms of Tc17 induction remain unclear. In this study, we focused on the pathogenic subsets… read more here.
Keywords: mcam; cd83; cd8 cells; cd161 ... See more keywords