RNA‐seq and ATAC‐seq analysis of CD163 + macrophage‐induced progestin‐insensitive endometrial cancer cells
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5396
Abstract: Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH). CD163+ macrophages promote estrogen‐dependent EEC development, but whether they induce progestin insensitivity remains unclear.… read more here.
Keywords: endometrial cancer; rna seq; cd163; seq atac ... See more keywords
CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.01.004
Abstract: ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe economic losses to current swine production worldwide. Highly pathogenic PRRSV (HP‐PRRSV), originated from a genotype 2 PRRSV, is more virulent than classical PRRSV and further… read more here.
Keywords: cd163 knockout; highly pathogenic; cd163; virus ... See more keywords
Defining molecular identity and fates of CNS-border associated macrophages after ischemic stroke in rodents and humans
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2019.104722
Abstract: Central nervous system (CNS)-border associated macrophages (BAMs) maintain their steady-state population during adulthood and are not replaced by circulating monocytes under physiological conditions. Their roles in CNS integrity and functions under pathological conditions remain largely… read more here.
Keywords: ischemic stroke; cd163 cells; cd163; border associated ... See more keywords
Prognostic significance of CD68+ and CD163+ tumor associated macrophages in head and neck squamous cell carcinoma: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2019.04.019
Abstract: OBJECTIVE Tumor associated macrophages (TAMs) are among the most abundant cells of the tumor microenvironment. Several studies have been performed to investigate whether TAM markers, namely CD68 and CD163, could serve as prognostic factors in… read more here.
Keywords: cd68 cd163; meta analysis; cd163; systematic review ... See more keywords
Immunohistochemical study of morphology and distribution of CD163+ve macrophages in the normal adult equine gastrointestinal tract.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2020.110073
Abstract: Intestinal macrophages are the largest group of mononuclear phagocytes in the body and play a role in intestinal innate immunity, neuroimmune interactions and maintaining intestinal homeostasis. Conversely, they also are implicated in numerous pathologies of… read more here.
Keywords: morphology distribution; gastrointestinal tract; cd163; equine gastrointestinal ... See more keywords
A porcine alveolar macrophage cell line stably expressing CD163 demonstrates virus replication and cytokine secretion characteristics similar to primary alveolar macrophages following PRRSV infection.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2020.108690
Abstract: The in vitro investigation of cytokine secretion induced by porcine reproductive and respiratory syndrome virus (PRRSV) requires porcine alveolar macrophages (PAMs) and their interaction with immunocytes. However, immortalized monoclonal PAMs (mPAMs) are non-permissive for PRRSV… read more here.
Keywords: cell line; cytokine secretion; prrsv infection; cd163 ... See more keywords
Genetically edited pigs lacking CD163 show no resistance following infection with the African swine fever virus isolate, Georgia 2007/1.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2016.11.012
Abstract: African swine fever is a highly contagious, often fatal disease of swine for which there is no vaccine or other curative treatment. The macrophage marker, CD163, is a putative receptor for African swine fever virus… read more here.
Keywords: swine fever; african swine; infection; georgia 2007 ... See more keywords
Expression of CD206 and CD163 on intermediate CD14++CD16+ monocytes are increased in hemorrhagic fever with renal syndrome and are correlated with disease severity.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.05.021
Abstract: BACKGROUND Hantaan virus infection causes lethal hemorrhagic fever with renal syndrome (HFRS) in humans. Little is known about how monocytes contribute to HFRS pathogenesis. In this study, we aimed to investigate changes in various monocyte… read more here.
Keywords: cd206; cd16; cd16 monocytes; cd163 ... See more keywords
CD163, a novel therapeutic target, regulates the proliferation and stemness of glioma cells via casein kinase 2
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DOI: 10.1038/s41388-018-0515-6
Abstract: Glioma is a devastating cancer with a dismal prognosis and there is an urgent need to discover novel glioma-specific antigens for glioma therapy. Previous studies have identified CD163-positive tumour cells in certain solid tumours, but… read more here.
Keywords: glioma; cd163; glioma cells; casein kinase ... See more keywords
S100A9/CD163 expression profiles in classical monocytes as biomarkers to discriminate idiopathic pulmonary fibrosis from idiopathic nonspecific interstitial pneumonia
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-91407-9
Abstract: Circulating monocytes have pathogenic relevance in idiopathic pulmonary fibrosis (IPF). Here, we determined whether the cell surface levels of two markers, pro-inflammatory-related S100A9 and anti-inflammatory-related CD163, expressed on CD14strongCD16− classical monocytes by flow cytometry could… read more here.
Keywords: s100a9 cd163; idiopathic pulmonary; cd163; pulmonary fibrosis ... See more keywords
Extracellular vesicle-associated soluble CD163 and CD206 in patients with acute and chronic inflammatory liver disease
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2020.1759140
Abstract: Abstract Background: Extracellular vesicles (EVs) are implicated in intercellular communication in liver diseases. An EV-associated fraction of the macrophage biomarker soluble CD163, denoted EV-CD163, was recently identified. EV-CD163 may be released during later phases of… read more here.
Keywords: patients acute; cd206 patients; liver; cd163 ... See more keywords