Phospholipase activity of acyloxyacyl hydrolase induces IL‐22‐producing CD1a‐autoreactive T cells in individuals with psoriasis
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202149485
Abstract: Psoriasis is a chronic inflammatory skin disease characterized by Th17 responses. Recent evidence has identified Langerhans cells to have a key role in disease pathogenesis, with constitutive high expression of CD1a and capacity to present… read more here.
Keywords: acyloxyacyl hydrolase; individuals psoriasis; cd1a; activity ... See more keywords
CD1a function in human skin disease.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.12.006
Abstract: The high expression of CD1a on Langerhans cells in normal human skin suggests a central role for this lipid antigen presenting molecule in skin homeostasis and immunity. Although the lipid antigen presenting function of CD1a… read more here.
Keywords: skin disease; function; skin; human skin ... See more keywords
Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20173-y
Abstract: Serotonin is a monoamine neurotransmitter that signals through a wide array of receptors (5-HT1–7) many of which are also involved in immune processes. Dendritic cells (DCs) are crucial players in immune defense by bridging innate… read more here.
Keywords: immunomodulatory capacity; ht2b; serotonin; dendritic cells ... See more keywords
Diagnostic usefulness of immunohistochemical evaluation of CD1a antigen and polyclonal anti-leishmania antibodies in cutaneous leishmaniasis.
Sign Up to like & getrecommendations! Published in 2021 at "Histology and histopathology"
DOI: 10.14670/hh-18-324
Abstract: BACKGROUND Different immunohistochemical markers to detect amastigotes in cutaneous leishmaniasis have been proposed with variable diagnostic usefulness. OBJECTIVES To evaluate the diagnostic usefulness of immunohistochemical amastigotes identification by specific polyclonal anti-Leishmania antibodies and CD1a expression… read more here.
Keywords: leishmania antibodies; anti cd1a; cd1a; leishmania ... See more keywords
Distribution of DC Subtypes: CD83+, DC-LAMP+, CD1a+, CD1c+, CD123+, and DC-SIGN+ in the Tumor Microenvironment of Endometrial Cancers—Correlation with Clinicopathologic Features
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031933
Abstract: Treatment options for endometrial cancer (EC) do not provide satisfactory survival improvement for advanced cases, hence the interest in novel therapies utilizing immunological regulatory mechanisms. Measures to modify the functionality of dendritic cells (DCs) found… read more here.
Keywords: cd1c cd123; cd1a; dcs; distribution subtypes ... See more keywords
Human Decidual CD1a+ Dendritic Cells Undergo Functional Maturation Program Mediated by Gp96
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032278
Abstract: Heat shock proteins (hsps), in certain circumstances, could shape unique features of decidual dendritic cells (DCs) that play a key role in inducing immunity as well as maintaining tolerance. The aim of the study was… read more here.
Keywords: maturation; cd1a; decidual cd1a; dendritic cells ... See more keywords