Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8+ invariant natural killer T cells.
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DOI: 10.1016/j.clim.2017.08.002
Abstract: Invariant natural killer T (iNKT) cells are cytotoxic T cells that respond to glycolipid antigens presented by CD1d. Therapeutic activation of iNKT cells with α-galactosylceramide (α-GalCer) can prevent and reverse tumor growth in mice and… read more here.
Keywords: cd1d expression; invariant natural; inkt cells; natural killer ... See more keywords