The prenatal challenge with lipopolysaccharide and polyinosinic:polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat offspring: a link to schizophrenia-like behaviours
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01923-0
Abstract: Background The bidirectional communication between neurons and microglia is fundamental for the homeostasis and biological function of the central nervous system. Maternal immune activation (MIA) is considered to be one of the factors affecting these… read more here.
Keywords: cd200 cd200r; mia; cx3cl1 cx3cr1; cx3cr1 cd200 ... See more keywords
CD200-CD200R Interaction: An Important Regulator After Stroke
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00840
Abstract: The high mortality and morbidity rate of stroke is a chronic problem that plagues human society. The activation of microglia is one of the principal reasons why neuroinflammation induces cerebral dysfunction. Because of their vital… read more here.
Keywords: interaction important; cd200r interaction; important regulator; cd200r ... See more keywords
Cancel cancer: The immunotherapeutic potential of CD200/CD200R blockade
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1088038
Abstract: Immune checkpoint molecules function to inhibit and regulate immune response pathways to prevent hyperactive immune activity from damaging healthy tissues. In cancer patients, targeting these key molecules may serve as a valuable therapeutic mechanism to… read more here.
Keywords: cd200; cd200 cd200r; cd200r; cd200r blockade ... See more keywords