Macrophage mannose receptor CD206 targeting of fluoride-18 labeled mannosylated dextran: A validation study in mice
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-024-06686-x
Abstract: Aluminum fluoride-18-labeled 1,4,7-triazacyclononane-1,4,7-triacetic acid-conjugated mannosylated dextran derivative (Al[18F]F-NOTA-D10CM) is a new tracer for PET imaging. We report here on in vitro and in vivo validation of the tracer’s ability to target the macrophage mannose receptor… read more here.
Keywords: mice; cd206; 18f nota; nota d10cm ... See more keywords
Expression of CD206 and CD163 on intermediate CD14++CD16+ monocytes are increased in hemorrhagic fever with renal syndrome and are correlated with disease severity.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.05.021
Abstract: BACKGROUND Hantaan virus infection causes lethal hemorrhagic fever with renal syndrome (HFRS) in humans. Little is known about how monocytes contribute to HFRS pathogenesis. In this study, we aimed to investigate changes in various monocyte… read more here.
Keywords: cd206; cd16; cd16 monocytes; cd163 ... See more keywords
Evaluation of a CD206-Targeted Peptide for PET Imaging of Macrophages in Syngeneic Mouse Models of Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00977
Abstract: Tumor-associated macrophages (TAMs) are large phagocytic cells that play numerous roles in cancer biology and are an important component of the relationship between immune system response and tumor progression. The peptide, RP832c, targets the Mannose… read more here.
Keywords: cd206; 68ga rp832c; tumor; cancer ... See more keywords
Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c10757
Abstract: The mannose receptor (CD206) is an endocytic receptor expressed by selected innate immune cells and nonvascular endothelium, which plays a critical role in both homeostasis and pathogen recognition. Although its involvement in the development of… read more here.
Keywords: vitro vivo; cd206; mannose receptor; receptor ... See more keywords
Divergent effects on macrophage biomarkers soluble CD163 and CD206 in axial spondyloarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2018.1500704
Abstract: Abstract The chronic joint inflammation in axial spondyloarthritis (axSpA) is characterized by infiltration of activated macrophages. The haptoglobin–hemoglobin receptor CD163 and the mannose receptor CD206 are strongly expressed on M2c and M2a macrophages, respectively. We… read more here.
Keywords: weeks iqr; cd206; anti tnf; iqr weeks ... See more keywords
Low lymphocyte-to-monocyte ratio, calcitriol level, and CD206 level predict the development of acute-on-chronic liver failure in patients cirrhosis with acute decompensation
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the Chinese Medical Association"
DOI: 10.1097/jcma.0000000000000867
Abstract: Background: Cirrhosis-related acute-on-chronic liver failure (ACLF) is associated with high morbidity and mortality rates. Prognostic models of ACLF have been developed; however, few studies have focused on the occurrence of ACLF. This study aimed to… read more here.
Keywords: cd206; development; patients cirrhosis; level ... See more keywords
Antibody combinations for optimized staining of macrophages in human lung tumours
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12889
Abstract: The analysis of tumour‐associated macrophages (TAMs) has a high potential to predict cancer recurrence and response to immunotherapy. However, the heterogeneity of TAMs poses a challenge for quantitative and qualitative measurements. Here, we critically evaluated… read more here.
Keywords: cd206; lung tumours; macrophage; cd163 cd206 ... See more keywords
FRI0404 Characterisation of a monocytes/macrophages cell subset co-expressing both m1 and m2 phenotype markers in systemic sclerosis patients
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6225
Abstract: Background In the pathogenesis of systemic sclerosis (SSc), the immune cell activation is an important event that includes alteration in the macrophage polarisation.1 Macrophages may polarise into classically activated (M1), which are characterised by the… read more here.
Keywords: monocytes macrophages; cd206; phenotype markers; cd163 cd206 ... See more keywords
OP0134 MACROPHAGES SKEWED BY GM-CSF PRODUCE YKL-40, INSTIGATING ANGIOGENESIS IN GIANT CELL ARTERITIS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.4455
Abstract: Background: Giant cell arteritis (GCA) is an inflammatory disease affecting the medium- and large-sized arteries. The pathology of GCA is characterized by an infiltrate of mainly CD4+ T-cells and macrophages. These macrophages release a wide… read more here.
Keywords: gca; cd206; none declared; ykl ... See more keywords
CD206+IL-4Rα+ Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/circulationaha.124.072411
Abstract: BACKGROUND The role of cardiac CD (cluster of differentiation) 206+ macrophages in chronic heart failure (HF) is unknown. We examined whether CD206+ macrophages expressing IL (interleukin)-4Rα are key drivers of adverse left ventricular (LV) remodeling… read more here.
Keywords: fibrosis; cd206; drivers adverse; cd206 macrophages ... See more keywords
Macrophage mannose receptor CD206-targeted PET imaging in experimental acute myocardial infarction
Sign Up to like & getrecommendations! Published in 2025 at "EJNMMI Research"
DOI: 10.1186/s13550-025-01254-2
Abstract: The macrophage mannose receptor (CD206) is expressed predominantly on the surface of M2-type macrophages, which play a role in resolution of inflammation after myocardial injury. The purpose of this study was to evaluate the utility… read more here.
Keywords: cd206; macrophage mannose; receptor cd206; 18f nota ... See more keywords