Emergence of the CD226 Axis in Cancer Immunotherapy
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DOI: 10.3389/fimmu.2022.914406
Abstract: In recent years, a set of immune receptors that interact with members of the nectin/nectin-like (necl) family has garnered significant attention as possible points of manipulation in cancer. Central to this axis, CD226, TIGIT, and… read more here.
Keywords: cd226 axis; biology; axis cancer; axis ... See more keywords
TIGIT/CD226 Axis Regulates Anti-Tumor Immunity
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DOI: 10.3390/ph14030200
Abstract: Tumors escape immune surveillance by inducing various immunosuppressive pathways, including the activation of inhibitory receptors on tumor-infiltrating T cells. While monoclonal antibodies (mAbs) blocking programmed cell death 1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic… read more here.
Keywords: immunity; cd226 axis; axis regulates; cancer ... See more keywords