Overview of CD24 as a new molecular marker in ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27581
Abstract: Ovarian cancer (OC) is the fifth leading cause of cancer‐related death among women. The high mortality rate is due to lack of early symptoms, late diagnosis, limited treatment options, and also emerging of drug resistance.… read more here.
Keywords: molecular marker; new molecular; marker; ovarian cancer ... See more keywords
Metalloprotease-dependent activation of EGFR modulates CD44+/CD24− populations in triple negative breast cancer cells through the MEK/ERK pathway
Sign Up to like & getrecommendations! Published in 2017 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-017-4440-0
Abstract: PurposeThe CD44+/CD24− cell phenotype is enriched in triple negative breast cancers, is associated with tumor invasive properties, and serves as a cell surface marker profile of breast cancer stem-like cells. Activation of Epidermal Growth Factor… read more here.
Keywords: egfr; cd24 populations; cd44 cd24; activation ... See more keywords
A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of dental sciences"
DOI: 10.1016/j.jds.2021.01.012
Abstract: Background/purpose CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum. But the comprehensive role of CD24 in… read more here.
Keywords: cells apical; stem cells; cd24; cd24 scaps ... See more keywords
Precise O-Glycosylation Site Localization of CD24Fc by LC-MS Workflows.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01137
Abstract: CD24Fc is a homodimeric recombinant Fc-fusion protein comprised of human CD24 connected to immunoglobulin G1 (IgG1) Fc fragment. CD24 is heavily glycosylated, and its biological function is considered mainly mediated by its glycosylation. Identification of… read more here.
Keywords: glycosylation site; precise glycosylation; glycosylation; glycosylation sites ... See more keywords
Targeted Intervention of NF2-YAP Signaling Axis in CD24-Overexpressing Cells Contributes to Encouraging Therapeutic Effects in TNBC.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c10921
Abstract: Triple-negative breast cancer (TNBC) cells have not been usefully classified, and no targeted therapeutic plans are currently available, resulting in a high recurrence rate and metastasis potential. In this research, CD24high cells accounted for the… read more here.
Keywords: nf2 yap; cd24high cells; yap signaling; signaling axis ... See more keywords
CD24 signalling through macrophage Siglec-10 is a new target for cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/s41586-019-1456-0
Abstract: Ovarian cancer and triple-negative breast cancer are among the most lethal diseases affecting women, with few targeted therapies and high rates of metastasis. Cancer cells are capable of evading clearance by macrophages through the overexpression… read more here.
Keywords: target cancer; cancer immunotherapy; macrophage; cd24 ... See more keywords
Progressive induction of hepatocyte progenitor cells in chronically injured liver
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep39990
Abstract: Differentiated epithelial cells show substantial lineage plasticity upon severe tissue injuries. In chronically injured mouse livers, part of hepatocytes become Sry-HMG box containing 9 (Sox9) (+) epithelial cell adhesion molecule (−) hepatocyte nuclear factor 4… read more here.
Keywords: sox9 hepatocytes; chronically injured; cd24; progenitor ... See more keywords
Cell surface glycoprotein CD24 marks bone marrow derived human mesenchymal stem/stromal cells with reduced proliferative and differentiation capacity in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cells and development"
DOI: 10.1089/scd.2021.0027
Abstract: Bone marrow-derived mesenchymal stem/stromal cells (BMSCs) are fundamental to bone regenerative therapies, tissue engineering, and postmenopausal osteoporosis. Donor variation among patients, cell heterogeneity and unpredictable capacity for differentiation reduce effectiveness of BMSCs for regenerative cell… read more here.
Keywords: capacity; differentiation; cd24; cell surface ... See more keywords
Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Reports"
DOI: 10.1101/2022.05.05.490732
Abstract: There is compelling evidence that cancer stem cells (CSCs) play an essential role in failure of conventional antitumor therapy. In breast cancer, CD24-/low/CD44+ phenotype as well as a high aldehyde dehydrogenase activity (ALDH+) are widely… read more here.
Keywords: cd24; cancer cells; breast cancer; resistance ... See more keywords
CD24 blockade promotes anti-tumor immunity in oral squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Oral diseases"
DOI: 10.1111/odi.14367
Abstract: OBJECTIVES Our study elucidates the prognostic role of cluster of differentiation (CD) 24 expression in oral squamous cell carcinoma (OSCC) and determines whether targeting CD24 enhances the anti-tumor immune response by inhibiting tumor-associated macrophages (TAMs).… read more here.
Keywords: cell carcinoma; anti tumor; squamous cell; tumor ... See more keywords
Abstract 1162: CD24 regulates cancer stem cell like traits in bladder cancer
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1162
Abstract: Tumors are hierarchically organized by a rare population of cancer stem cells (CSCs) that contributes to cancer initiation, progression, and treatment failure. A better understanding of the molecular mechanisms underlying urothelial CSC regulation and the… read more here.
Keywords: cd24 regulates; cancer; like traits; cd24 ... See more keywords