Low expressions of PD-L1 and CTLA-4 by induced CD4+CD25+ Foxp3+ Tregs in patients with SLE and their correlation with the disease activity.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155119
Abstract: BACKGROUND The induction of CD4+CD25+Foxp3+ Treg from CD4+CD25- T cells is deficient in the patients with systemic lupus erythematosus (SLE). Whether the induced CD4+CD25+Foxp3+ Tregs possess defective function remains unclear. The purpose of the present… read more here.
Keywords: cd4 cd25; induced cd4; cd25; cd25 foxp3 ... See more keywords
Effect of adoptive transfer of CD4+CD25+Foxp3+ Treg induced by trichostatin A on the prevention of spontaneous abortion.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2018.12.002
Abstract: OBJECTIVE To investigate whether epigenetic modification of CD4+CD25- T-cells in vitro can make up for the inadequacy of CD4+CD25+Foxp3+ Treg in animal model of spontaneous abortion and prevent immune response-mediated spontaneous abortion. METHODS Trichostatin A… read more here.
Keywords: cd4 cd25; foxp3 treg; cd4; cd25 foxp3 ... See more keywords
Acceleratory effects of ambient fine particulate matter on the development and progression of atherosclerosis in apolipoprotein E knockout mice by down-regulating CD4+CD25+Foxp3+ regulatory T cells.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.09.005
Abstract: OBJECTIVE Atherosclerosis is an autoimmune inflammatory disease that is closely associated with long-term exposure to fine particulate matter (PM2.5). CD4+CD25+Foxp3+ regulatory T cells (Tregs) play a critical role in the regulation of T cell-mediated immune… read more here.
Keywords: cd4 cd25; pm2; atherosclerosis; cd25 foxp3 ... See more keywords
Multiple sclerosis patients have reduced resting and increased activated CD4+CD25+FOXP3+T regulatory cells
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-88448-5
Abstract: Resting and activated subpopulations of CD4+CD25+CD127loT regulatory cells (Treg) and CD4+CD25+CD127+ effector T cells in MS patients and in healthy individuals were compared. Peripheral blood mononuclear cells isolated using Ficoll Hypaque were stained with monoclonal… read more here.
Keywords: cd4 cd25; cd25; treg; population ... See more keywords
Progesterone modulates CD4+CD25+FoxP3+ regulatory T Cells and TGF‐β1 in the maternal‐fetal interface of the late pregnant mouse
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13541
Abstract: Progesterone supplementation is recommended to prevent spontaneous preterm birth (sPTB) in clinical practice. However, the exact mechanism is still unclear. This study aims to better understand the mechanisms that progesterone can prevent PTB. read more here.
Keywords: foxp3 regulatory; cd25 foxp3; cd4 cd25; modulates cd4 ... See more keywords
Correlation of Blood FoxP3+ Regulatory T Cells and Disease Activity of Atopic Dermatitis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Immunology Research"
DOI: 10.1155/2019/1820182
Abstract: Objectives To investigate CD4+CD25+FoxP3+ T regulatory cells (Tregs) in the peripheral blood of patients with atopic dermatitis (AD) and its correlation with disease severity. Methods Blood samples from 79 AD patients before and after four-week… read more here.
Keywords: cd4 cd25; correlation; foxp3; cd25 foxp3 ... See more keywords
The relation of CD4+CD25+Foxp3+ regulatory T cells concentration with disease activity and damage index in systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2022 at "Lupus"
DOI: 10.1177/09612033221083269
Abstract: Introduction Regulatory T cells (Treg) deficits, both quantitative and qualitative, are known to be possible triggers for the development of autoimmune disorders by causing T and B cells dysfunction. The contribution of Treg deficiency in… read more here.
Keywords: cd4 cd25; cd25 foxp3; damage;
Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4+CD25+Foxp3+ and CD4+CD25−Foxp3+ T cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-019-1967-3
Abstract: BackgroundThe pleiotropic cytokine, transforming growth factor (TGF)-β, and CD4+CD25+Foxp3+ regulatory T cells (Tregs) play a critical role in actively suppressing antitumor immune responses. Evidence shows that TGF-β produced by tumor cells promotes tolerance via expansion… read more here.
Keywords: cd4 cd25; tgf; cd4; cd25 foxp3 ... See more keywords
Age-related changes in CD4+CD25+FOXP3+ regulatory T cells and their relationship with lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0173048
Abstract: Objectives CD4+CD25+FOXP3+ regulatory T cells (Treg) inhibit the anti-tumour immune response and reduce the effect of cancer immunotherapy. Although studies have demonstrated that the number and suppressive activity of Treg increase with age, it is… read more here.
Keywords: cd4 cd25; foxp3; cd25 foxp3; lung cancer ... See more keywords
Immune Tolerance of Human Dental Pulp-Derived Mesenchymal Stem Cells Mediated by CD4+CD25+FoxP3+ Regulatory T-Cells and Induced by TGF-β1 and IL-10
Sign Up to like & getrecommendations! Published in 2017 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2017.58.5.1031
Abstract: Purpose Most studies on immune tolerance of mesenchymal stem cells (MSCs) have been performed using MSCs derived from bone marrow, cord blood, or adipose tissue. MSCs also exist in the craniofacial area, specifically in teeth.… read more here.
Keywords: tolerance; cd4 cd25; immune tolerance; dental pulp ... See more keywords