Lung infection caused by Pseudomonas aeruginosa in a CD26/DPP4 deficient F344 rat model
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation Research"
DOI: 10.1007/s00011-019-01236-w
Abstract: BackgroundPseudomonas aeruginosa (PA) is the most important opportunistic pathogen in causing nosocomial infections and, furthermore, poses a permanent threat for severe chronic infections in patients with cystic fibrosis or COPD. The transmembrane protein CD26 with… read more here.
Keywords: dpp4; lung infection; cd26; cd26 dpp4 ... See more keywords
CD26/DPP4 levels in peripheral blood and T cells in Hashimoto's thyroiditis with normal thyroid function.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105941
Abstract: AIMS Exploring the CD26 expression in peripheral blood and T cells in Hashimoto's thyroiditis with normal thyroid function. And evaluating the association between CD26 expression and TGAb and TPOAb levels. METHODS We collected peripheral blood… read more here.
Keywords: normal thyroid; peripheral blood; cd26; thyroid function ... See more keywords
A novel chimeric antigen receptor redirecting T-cell specificity towards CD26+ cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0824-y
Abstract: Chimeric antigen receptor (CAR) T-cell immunotherapy is rapidly emerging as a promising novel treatment for malignancies. To broaden the success of CAR T-cell treatment for chronic myeloid leukaemia (CML), we attempted to construct a CD26… read more here.
Keywords: cell; cd26; antigen receptor; car ... See more keywords
Expansion of different subpopulations of CD26−/low T cells in allergic and non-allergic asthmatics
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-43622-8
Abstract: CD26 displays variable levels between effector (TH17 ≫ TH1 > TH2 > Treg) and naïve/memory (memory > naïve) CD4+ T lymphocytes. Besides, IL-6/IL−6R is associated with TH17-differentiation and asthma severity. Allergic/atopic asthma (AA) is dominated by TH2 responses, while TH17 immunity might either… read more here.
Keywords: allergic non; low cells; cd26 low; expansion ... See more keywords
CD4+ T cells in classical Hodgkin lymphoma express exhaustion associated transcription factors TOX and TOX2
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2033433
Abstract: ABSTRACT In classical Hodgkin lymphoma (cHL), the highly abundant CD4+ T cells in the vicinity of tumor cells are considered essential for tumor cell survival, but are ill-defined. Although they are activated, they consistently lack… read more here.
Keywords: cell; cd26; classical hodgkin; cd4 ... See more keywords
Involvement of CD26 in Differentiation and Functions of Th1 and Th17 Subpopulations of T Lymphocytes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Immunology Research"
DOI: 10.1155/2021/6671410
Abstract: CD26, acting as a costimulator of T cell activation, plays an important role in the immune system. However, the role of CD26 in the differentiation of T cell subsets, especially of new paradigms of T… read more here.
Keywords: cd26 differentiation; th1 th17; differentiation; cd26 ... See more keywords
Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0218330
Abstract: A 110-kDa type II transmembrane glycoprotein with dipeptidyl peptidase IV (DPPIV) activity in its extracellular region, CD26 has a multitude of biological functions and plays an important role in the regulation of inflammatory responses and… read more here.
Keywords: fixed paraffin; paraffin embedded; formalin fixed; denatured human ... See more keywords
CD26 Inhibition Potentiates the Therapeutic Effects of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells by Delaying Cellular Senescence
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.803645
Abstract: Mesenchymal stem cells (MSCs) are recognized as potential treatments for multiple degenerative and inflammatory disorders as a number of animal and human studies have indicated their therapeutic effects. There are also several clinically approved medicinal… read more here.
Keywords: cd26; mesenchymal stem; cellular senescence; mscs ... See more keywords
Mapping Salivary Proteases in Sjögren’s Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.686480
Abstract: Sjögren’s Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration. Identifying new non-invasive biomarkers for SS diagnosis remains a challenge, and alterations in saliva… read more here.
Keywords: gren syndrome; peptidase cd26; cd26; dipeptidyl peptidase ... See more keywords
Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.832989
Abstract: Several serine proteases have been linked to autoimmune disorders and tumour initiation although the mechanisms are not fully understood. Activation of the kynurenine pathway enzyme indoleamine-2,3-dioxygenase (IDO1) modulates cellular activity in the brain, tolerogenesis in… read more here.
Keywords: prostate specific; cd26; specific antigen; ido1 ... See more keywords
Analysis of Common Beta-Thalassemia (β-Thalassemia) Mutations in East Java, Indonesia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.925599
Abstract: Background The frequency of the beta-thalassemia (β-thalassemia) gene in Indonesia ranges from 3 to 10%. However, in the East Java province, there is still limited information on the prevalence of β-thalassemia mutations in clinically diagnosed… read more here.
Keywords: cd26; thalassemia; beta thalassemia; east java ... See more keywords