Comparative characterization of CD271+ and CD271− subpopulations of CD34+ human adipose‐derived stromal cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26496
Abstract: Adipose‐derived stromal/stem cells (ASCs) are promising candidates for cell‐based therapies. However, the lack of markers able to unequivocally identify these cells, the differential expression of cell surface molecules among stromal progenitors from different tissues and… read more here.
Keywords: human adipose; derived stromal; cd271; expression ... See more keywords
CD271 determines migratory properties of melanoma cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10129-z
Abstract: Melanoma cell expression of the nerve growth factor receptor CD271 is associated with stem-like properties. However, the contributing role of the receptor in melanoma cell migration is elusive. Here, we explored extracranial (skin, soft tissue,… read more here.
Keywords: melanoma; melanoma cell; cd271; migration ... See more keywords
CD271 mRNA/hnRNPA2B1 complex promotes proliferation and stemness in oral and head and neck squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Science"
DOI: 10.1111/cas.16187
Abstract: RNAs, such as noncoding RNA, microRNA, and recently mRNA, have been recognized as signal transduction molecules. CD271, also known as nerve growth factor receptor, has a critical role in cancer, although the precise mechanism is… read more here.
Keywords: cd271; cd271 mrna; protein; squamous cell ... See more keywords
Cell viability and chemotherapeutic resistance across melanoma lines from various stages of progression
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.2501
Abstract: Background: The melanoma stem cell (MSC) hypothesis holds that a subpopulation of cells with stem-cell like features are important for tumor progression and chemoresistance. We examined four V600E BRAF-mutated melanoma lines at various stages of… read more here.
Keywords: cd271; physiology; melanoma; cell ... See more keywords
CD271+ Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH Medulloblastoma.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-0027
Abstract: The extensive heterogeneity both between and within the medulloblastoma subgroups underscores a critical need for variant-specific biomarkers and therapeutic strategies. We previously identified a role for the CD271/p75 neurotrophin receptor (p75NTR) in regulating stem/progenitor cells… read more here.
Keywords: diagnostic prognostic; shh medulloblastoma; medulloblastoma; cd271 ... See more keywords
Reactive Oxygen Species Regulation of Chemoresistance and Metastatic Capacity of Melanoma: Role of the Cancer Stem Cell Marker CD271
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041229
Abstract: BRAF mutations are present in 30–50% of cases of cutaneous melanoma, and treatment with selective BRAF and MEK inhibitors has been introduced. However, the development of resistance to these drugs often occurs. Chemo-resistant melanoma cells… read more here.
Keywords: reactive oxygen; cd271; stem cell; melanoma ... See more keywords