Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4+ T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.915963
Abstract: Costimulatory molecules of the CD28 family play a crucial role in the activation of immune responses in T lymphocytes, complementing and modulating signals originating from the T-cell receptor (TCR) complex. Although distinct functional roles have… read more here.
Keywords: icos cd28; cd28 costimulatory; cd4 cells; cd28 ... See more keywords
Zinc Ionophore Pyrithione Mimics CD28 Costimulatory Signal in CD3 Activated T Cells
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25084302
Abstract: Zinc is an essential trace element that plays a crucial role in T cell immunity. During T cell activation, zinc is not only structurally important, but zinc signals can also act as a second messenger.… read more here.
Keywords: differentiation; cd3; cd28 costimulatory; zinc ... See more keywords