Structures of Immune Checkpoints: An Overview on the CD28-B7 Family.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-9367-9_3
Abstract: The co-stimulation and co-inhibition signal pathways, immune checkpoints, are among the central mechanisms to regulate the T-cell immunity. Optimal signals involve intricate interactions of numerous ligands and receptors. Manipulation of these signals offers great clinical… read more here.
Keywords: medicine; structures immune; cancer; immune checkpoints ... See more keywords
Costimulatory and coinhibitory molecules of B7-CD28 family in cardiovascular atherosclerosis: A review
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031667
Abstract: Accumulating evidence supports the active involvement of vascular inflammation in atherosclerosis pathogenesis. Vascular inflammatory events within atherosclerotic plaques are predominated by innate antigen-presenting cells (APCs), including dendritic cells, macrophages, and adaptive immune cells such as… read more here.
Keywords: atherosclerosis review; cd28 family; family; costimulatory coinhibitory ... See more keywords
Inborn errors of immunity associated with defects of selfâtolerance checkpoints: The CD28 family
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13886
Abstract: One of the causes of inborn errors of immunity is immune dysregulation. The inability of the immune system to regulate the extent of its activity has several deleterious effects, including autoimmunity, recurrent infections, and malignancy.… read more here.
Keywords: immunity associated; cd28 family; errors immunity; inborn errors ... See more keywords