Articles with "cd3 affinity" as a keyword



Dichotomous impact of affinity on the function of T cell engaging bispecific antibodies

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Published in 2021 at "Journal for Immunotherapy of Cancer"

DOI: 10.1136/jitc-2021-002444

Abstract: Background Bispecific T cell engagers represent the majority of bispecific antibodies (BsAbs) entering the clinic to treat metastatic cancer. The ability to apply these agents safely and efficaciously in the clinic, particularly for solid tumors,… read more here.

Keywords: cell engaging; engaging bsabs; affinity; cd3 affinity ... See more keywords