Articles with "cd3 cd137" as a keyword



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Abstract 1872: A DLL3/CD3/CD137 trispecific T cell engager shows potent antitumor activity in small cell lung cancer models

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-1872

Abstract: Background: Despite the approval of immune checkpoint inhibitors (ICIs), prognosis of small cell lung cancer (SCLC) remains poor. DLL3 is upregulated in SCLC whereas expression in normal tissues is minimal, representing the favorable profile as… read more here.

Keywords: cd3 cd137; dll3; cell; dll3 trispecific ... See more keywords