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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22025
Abstract: Binding of programmed death-1 (PD-1) with its ligands (PD-L1/2) transmits a co-inhibitory signal in activated T-cells that promotes T-cell exhaustion, leading to tumor immune evasion. The efficacy of antibodies targeting PD-1 and PD-L1 has led…
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Keywords:
cd3;
cd3 cd3;
expression peripheral;
cd3 cd8 ... See more keywords