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   Articles with "cd3 cd8" as a keyword



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Frequencies of PD-1- positive T CD3+CD4+, T CD3+CD8+ and B CD19+ lymphocytes in female patients with Graves' disease and healthy controls– preliminary study

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recommendations! Published in 2017 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2017.03.006

Abstract: PD-1 maintains tolerance and inhibits autoimmune responses. Graves' disease (GD) is one of the most frequent autoimmune diseases of unclear etiology. The aim of this study was to evaluate the percentage and absolute counts of… read more here.

Keywords: cd3; cd3 cd4; study; cd3 cd8 ... See more keywords
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The Prognostic Value of Tumor-Infiltrating lymphocytes in Stage II Colon Cancer. A Nationwide Population-Based Study1

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recommendations! Published in 2018 at "Translational Oncology"

DOI: 10.1016/j.tranon.2018.03.008

Abstract: BACKGROUND: Additional prognostic markers are needed for better treatment stratification of stage II colon cancer (CC). We investigated the prognostic value of tumor-infiltrating lymphocytes (TILs) in a true population-based cohort of patients with stage II… read more here.

Keywords: prognostic value; cd8 tils; cd3 cd8; stage ... See more keywords
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Prognostic value of immunoscore to identify mortality outcomes in adults with HBV-related primary hepatocellular carcinoma

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recommendations! Published in 2017 at "Medicine"

DOI: 10.1097/md.0000000000006735

Abstract: Abstract This study aimed to determine if the immunoscore (IS) staging system would be a potential prognostic factor in hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) in China. IS was performed in a consecutive cohort of… read more here.

Keywords: hepatocellular carcinoma; hbv hcc; cd45ro; immunoscore ... See more keywords
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743 High levels of stromal tumor infiltrating lymphocytes, CD3, CD8 cells & Immunoscore® are associated with pathological CR and time to progression in TNBC patients undergoing neo-adjuvant chemotherapy

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recommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"

DOI: 10.1136/jitc-2020-sitc2020.0743

Abstract: Background The presence of high levels of stromal tumor infiltrating lymphocytes (TILs) has been associated with better prognosis in early triple-negative breast cancer (TNBC). The Immunoscore® (IS) is a prognostic tool, which categorizes the densities… read more here.

Keywords: patients patients; tnbc patients; cd8; high levels ... See more keywords
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Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinoma

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recommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"

DOI: 10.1136/jitc-2021-004031

Abstract: Background Hepatocellular carcinoma (HCC) is a highly lethal cancer and the second leading cause of cancer-related deaths worldwide. As demonstrated in other solid neoplasms and HCC, infiltrating CD8+ T cells seem to be related to… read more here.

Keywords: necroptosis; ripk3 mlkl; ripk1 ripk3; cd3 cd8 ... See more keywords
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Intertumoral Heterogeneity of CD3+ and CD8+ T-Cell Densities in the Microenvironment of DNA Mismatch-Repair–Deficient Colon Cancers: Implications for Prognosis

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recommendations! Published in 2018 at "Clinical Cancer Research"

DOI: 10.1158/1078-0432.ccr-18-1984

Abstract: Purpose: Colorectal cancers with deficient DNA mismatch repair (dMMR) are presumed to uniformly have dense lymphocytic infiltration that underlies their favorable prognosis and is critical to their responsiveness to immunotherapy, as compared with MMR-proficient (pMMR)… read more here.

Keywords: heterogeneity; dmmr; cell densities; pmmr ... See more keywords
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The prognostic impact of CD3, CD8, FoxP3, and IL17 tumor-infiltrating immune cells in periampullary cancer differs by morphological type and adjuvant chemotherapy.

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recommendations! Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.7_suppl.53

Abstract: 53Background: The prognostic impact of tumor-infiltrating T lymphocytes has been evaluated in periampullary carcinoma, but previous studies have not taken into consideration the different morphological subtypes of cancers derived from the periampullary region. Herein, we… read more here.

Keywords: tumor infiltrating; cd3 cd8; type; prognostic impact ... See more keywords
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High tissue expression of TLRs combined with high density of tumor infiltrating lymphocytes predicts a better prognosis in colorectal cancer patients

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recommendations! Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0280085

Abstract: Background Colorectal cancer causes 935,000 cancer deaths yearly. High local immune cell infiltration serves as a positive prognostic factor in CRC. Toll-like receptors (TLRs) induce innate immune responses and lead to adaptive immune system activation.… read more here.

Keywords: cd3; density; cd3 cd8; cancer ... See more keywords
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Expression of PD-1/PD-L1 and PD-L2 in peripheral T-cells from non-small cell lung cancer patients

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.22025

Abstract: Binding of programmed death-1 (PD-1) with its ligands (PD-L1/2) transmits a co-inhibitory signal in activated T-cells that promotes T-cell exhaustion, leading to tumor immune evasion. The efficacy of antibodies targeting PD-1 and PD-L1 has led… read more here.

Keywords: cd3; cd3 cd3; expression peripheral; cd3 cd8 ... See more keywords
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An Immunoscore System Based On CD3+ And CD8+ Infiltrating Lymphocytes Densities To Predict The Outcome Of Patients With Colorectal Adenocarcinoma

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recommendations! Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s211048

Abstract: Purpose The aim of this study was to evaluate the Immunoscore (IS) methodology as a prognostic marker of colorectal adenocarcinoma in Tunisian population. Tumor blocks were retrospectively collected from 106 patients with sporadic colorectal cancer.… read more here.

Keywords: infiltrating lymphocytes; colorectal adenocarcinoma; methodology; cd3 cd8 ... See more keywords
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Imbalance of Circulating Th17 and Regulatory T Cells in Alzheimer’s Disease: A Case Control Study

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recommendations! Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.01213

Abstract: The neuropathological hallmarks of Alzheimer’s disease (AD), i.e., neuritic plaques and neurofibrillary tangles, consist of beta amyloid peptides (Aβ) and hyperphosphorylated Tau. These are accompanied by reactive microglia and astrocytes in the vicinity of the… read more here.

Keywords: 17a ifn; control study; alzheimer disease; cd3 cd8 ... See more keywords