Low levels of CD3 + and CD8 + T cells in peripheral blood can predict poor efficacy of first-line chemotherapy in patients with angioimmunoblastic T cell lymphoma
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DOI: 10.1007/s00277-025-06314-0
Abstract: To investigate the prognostic significance of lymphocyte subsets in newly diagnosed angioimmunoblastic T-cell lymphoma (AITL) patients and track the dynamic changes in these subsets during treatment. We retrospectively analyzed the medical records in 56 patients… read more here.
Keywords: treatment; cd3 cd8; cell lymphoma; cell ... See more keywords
Frequencies of PD-1- positive T CD3+CD4+, T CD3+CD8+ and B CD19+ lymphocytes in female patients with Graves' disease and healthy controls– preliminary study
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DOI: 10.1016/j.mce.2017.03.006
Abstract: PD-1 maintains tolerance and inhibits autoimmune responses. Graves' disease (GD) is one of the most frequent autoimmune diseases of unclear etiology. The aim of this study was to evaluate the percentage and absolute counts of… read more here.
Keywords: cd3; cd3 cd4; study; cd3 cd8 ... See more keywords
The Prognostic Value of Tumor-Infiltrating lymphocytes in Stage II Colon Cancer. A Nationwide Population-Based Study1
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DOI: 10.1016/j.tranon.2018.03.008
Abstract: BACKGROUND: Additional prognostic markers are needed for better treatment stratification of stage II colon cancer (CC). We investigated the prognostic value of tumor-infiltrating lymphocytes (TILs) in a true population-based cohort of patients with stage II… read more here.
Keywords: prognostic value; cd8 tils; cd3 cd8; stage ... See more keywords
Artificial intelligence-based analysis of tumor-infiltrating lymphocyte spatial distribution for colorectal cancer prognosis
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DOI: 10.1097/cm9.0000000000002964
Abstract: Abstract Background: Artificial intelligence (AI) technology represented by deep learning has made remarkable achievements in digital pathology, enhancing the accuracy and reliability of diagnosis and prognosis evaluation. The spatial distribution of CD3+ and CD8+ T… read more here.
Keywords: cd3 cd8; prognosis; spatial distribution;
Prognostic value of immunoscore to identify mortality outcomes in adults with HBV-related primary hepatocellular carcinoma
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DOI: 10.1097/md.0000000000006735
Abstract: Abstract This study aimed to determine if the immunoscore (IS) staging system would be a potential prognostic factor in hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) in China. IS was performed in a consecutive cohort of… read more here.
Keywords: hepatocellular carcinoma; hbv hcc; cd45ro; immunoscore ... See more keywords
743 High levels of stromal tumor infiltrating lymphocytes, CD3, CD8 cells & Immunoscore® are associated with pathological CR and time to progression in TNBC patients undergoing neo-adjuvant chemotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0743
Abstract: Background The presence of high levels of stromal tumor infiltrating lymphocytes (TILs) has been associated with better prognosis in early triple-negative breast cancer (TNBC). The Immunoscore® (IS) is a prognostic tool, which categorizes the densities… read more here.
Keywords: patients patients; tnbc patients; cd8; high levels ... See more keywords
Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinoma
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DOI: 10.1136/jitc-2021-004031
Abstract: Background Hepatocellular carcinoma (HCC) is a highly lethal cancer and the second leading cause of cancer-related deaths worldwide. As demonstrated in other solid neoplasms and HCC, infiltrating CD8+ T cells seem to be related to… read more here.
Keywords: necroptosis; ripk3 mlkl; ripk1 ripk3; cd3 cd8 ... See more keywords
Intertumoral Heterogeneity of CD3+ and CD8+ T-Cell Densities in the Microenvironment of DNA Mismatch-Repair–Deficient Colon Cancers: Implications for Prognosis
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DOI: 10.1158/1078-0432.ccr-18-1984
Abstract: Purpose: Colorectal cancers with deficient DNA mismatch repair (dMMR) are presumed to uniformly have dense lymphocytic infiltration that underlies their favorable prognosis and is critical to their responsiveness to immunotherapy, as compared with MMR-proficient (pMMR)… read more here.
Keywords: heterogeneity; dmmr; cell densities; pmmr ... See more keywords
Abstract PO5-06-06: Tumor/stromal expression of CD3/CD8/PD-1/PD-L1 and overall survival (OS) in patients (pts) with metastatic (met) HER2+ breast cancer (BC)
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DOI: 10.1158/1538-7445.sabcs23-po5-06-06
Abstract: Background: The “Thousand Patient HER-2 database” project at Saint Vincent’s University Hospital (SVUH) Dublin contains a cohort of met HER2+ BC pts treated with trastuzumab, with OS ranging from short term to durable complete response… read more here.
Keywords: expression; tumor; cd3 cd8; met her2 ... See more keywords
Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases
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DOI: 10.1186/s40478-025-01939-8
Abstract: Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) have increasingly been reported to impact the brain metastatic process of solid tumors. However, data on intra-individual differences between primary tumor and brain metastasis (BM), as well as… read more here.
Keywords: cd3 cd8; brain metastases; tumor; primary tumor ... See more keywords
The prognostic impact of CD3, CD8, FoxP3, and IL17 tumor-infiltrating immune cells in periampullary cancer differs by morphological type and adjuvant chemotherapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.7_suppl.53
Abstract: 53Background: The prognostic impact of tumor-infiltrating T lymphocytes has been evaluated in periampullary carcinoma, but previous studies have not taken into consideration the different morphological subtypes of cancers derived from the periampullary region. Herein, we… read more here.
Keywords: tumor infiltrating; cd3 cd8; type; prognostic impact ... See more keywords