CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-019-0275-4
Abstract: Natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC) through CD16 plays a critical role in antihuman immunodeficiency virus (HIV) responses. CD300a is a surface receptor highly expressed on NK cells that has the capacity to… read more here.
Keywords: cd300a; infected patients; expression; cell ... See more keywords
CD300a identifies a CD4+ memory T cell subset with a higher susceptibility to HIV-1 infection.
Sign Up to like & getrecommendations! Published in 2020 at "AIDS"
DOI: 10.1097/qad.0000000000002544
Abstract: Human CD300a is known to promote the infection by Dengue and other enveloped viruses and is overexpressed on CD4+ T cells from HIV-1 infected patients. We found that infected CD4+RA- T cells from untreated HIV-1… read more here.
Keywords: hiv infection; susceptibility hiv; cd300a; infection ... See more keywords
CD300a contributes to the resolution of articular inflammation triggered by MSU crystals by controlling neutrophil apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1111/imm.13371
Abstract: Gout is an inflammatory disease triggered by deposition of monosodium urate (MSU) crystals in the joints, resulting in high neutrophil influx and pain. Here, we studied the role of the inhibitory receptor CD300a in the… read more here.
Keywords: resolution; cd300a; cd300a mice; msu crystals ... See more keywords
CD300a Regulates Mouse Macrophage Functionality in Allergic Inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "International archives of allergy and immunology"
DOI: 10.1159/000529606
Abstract: BACKGROUND CD300a is an inhibitory receptor (IR) expressed on several leukocytes, including mast cells (MCs) and macrophages (MΦ), important cells in allergic inflammation (AI). We have previously characterized CD300a role on MCs and in vivo… read more here.
Keywords: cd300a; absence; allergic inflammation; resolution ... See more keywords