CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12549
Abstract: Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic antibodies requires careful characterization of… read more here.
Keywords: myeloid leukemia; monocytic differentiation; cd300f; acute myeloid ... See more keywords
Astrocytic Expression of the Immunoreceptor CD300f Protects Hippocampal Neurons from Amyloid-β Oligomer Toxicity In Vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Current Alzheimer research"
DOI: 10.2174/1567205014666170202121709
Abstract: BACKGROUND Astrocytes contribute to neuroinflammation that accompanies neurodegenerative disorders such as Alzheimer's disease (AD). In this sense, the toxicity of these diseases might be attenuated through the modulation of astrocytic inflammatory responses. Recently, the CD300f… read more here.
Keywords: hippocampal neurons; protects hippocampal; immunoreceptor; toxicity ... See more keywords