Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators.
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DOI: 10.1021/acsmedchemlett.1c00396
Abstract: CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. Multiple genome-wide association studies (GWAS) have identified genetic variants in the CD33 gene that convey protection from late-onset Alzheimer's… read more here.
Keywords: cd33 pre; pre mrna; cd33; mrna ... See more keywords