Protective effect of microRNA‐134‐3p on multiple sclerosis through inhibiting PRSS57 and promotion of CD34+ cell proliferation in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29643
Abstract: MicroRNAs (miRs) have been extensively studied for their involvement in multiple sclerosis (MS). We investigated the involvement of miR‐134‐3p on MS. The MS rat model was established, and positive expression of interleukin‐17 (IL‐17) was detected… read more here.
Keywords: cd34 cell; cell proliferation; prss57; mir 134 ... See more keywords
CD34 + cell therapy significantly reduces adverse cardiac events, health care expenditures, and mortality in patients with refractory angina
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.20-0046
Abstract: Patients with refractory angina who are suboptimal candidates for further revascularization have improved exercise time, decreased angina frequency, and reduced major adverse cardiac events with intramyocardial delivery of CD34+ cells. However, the effect of CD34+… read more here.
Keywords: cd34 cell; cd34; cell therapy; refractory angina ... See more keywords
Mobilized Peripheral Blood Stem Cells Collection, a Retrospective Review of the Impact of Race/Ethnicity Among Autologous and Allogeneic Donors: A Single Center Experience
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.321
Abstract: The impact of race/ethnicity on hematopoietic stem/progenitor cell (HSPC) mobilization remains controversial. Past studies have concluded Black healthy donors as more robust mobilizers or comparable mobilizers with Whites in response to granulocyte colony-stimulating factor (G-CSF).… read more here.
Keywords: cd34 cell; race ethnicity; cd34; allogeneic donors ... See more keywords
Low CD45 mean fluorescence intensity predicts poor Post-Thaw CD34 cell viability
Sign Up to like & getrecommendations! Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.03.093
Abstract: Background & Aim Background Reduced CD34 cell viability following cryopreservation is associated with suboptimal engraftment in stem cell transplantation. Collection of extra hematopoietic progenitor cells (HPC) can compensate for the potential loss, but subjects patients… read more here.
Keywords: cd34 cell; cd34; post thaw;
Characteristics of cells with engraftment capacity within CD34+ cell population upon G-CSF and Plerixafor mobilization
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0982-y
Abstract: In the context of hematopoietic cell transplantation, hematopoietic stem cells and progenitor cells (HSC and HPC) are usually collected by apheresis following their mobilization by G-CSF alone or in combination with Plerixafor® when patients fail… read more here.
Keywords: cd34 cell; capacity; within cd34; csf ... See more keywords
Highly specific functional equivalence of XN-HPC for optimum CD34+ cell count in harvested allogeneic bone marrow stem cell products
Sign Up to like & getrecommendations! Published in 2022 at "Hematology"
DOI: 10.1080/16078454.2022.2030884
Abstract: ABSTRACT Objectives To establish a reliable XN-HPC cutoff, for an effective CD34 + cell count of ≥2 × 106cells/kg of the recipient’s body weight, in harvested bone marrow products in allogenic transplantation. Methods The study was carried out in… read more here.
Keywords: cell count; cell; cd34; body weight ... See more keywords
DNA Methylation and Hydroxymethylation Profile of CD34+-Enriched Cell Products Intended for Autologous CD34+ Cell Transplantation.
Sign Up to like & getrecommendations! Published in 2017 at "DNA and cell biology"
DOI: 10.1089/dna.2017.3729
Abstract: Epigenetic dysregulation has been shown to limit functional capacity of aging hematopoietic stem cells, which may contribute to impaired outcome of hematopoietic stem cell-based therapies. The aim of our study was to gain better insight… read more here.
Keywords: cd34 cell; cd34; methylation; dna ... See more keywords
Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials
Sign Up to like & getrecommendations! Published in 2018 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehx764
Abstract: Aims Autologous CD34+ (auto-CD34+) cells represent an attractive option for the treatment of refractory angina. Three double-blinded randomized trials (n = 304) compared intramyocardial (IM) auto-CD34+ cells with IM placebo injections to affect total exercise time (TET),… read more here.
Keywords: cd34 cell; cd34; cell therapy; auto cd34 ... See more keywords
Impact of CD34+ cell dose on reduced intensity conditioning regimen haploidentical hematopoietic stem cell transplantation
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Haematology"
DOI: 10.1111/ejh.13332
Abstract: Haploidentical hematopoietic stem cell transplant (haplo‐SCT) has been associated with higher rates of graft rejection, and a higher dose of CD34+ cell dose is frequently requested. We aim to explore the impact of CD34+ cell… read more here.
Keywords: cd34 cell; haploidentical hematopoietic; stem cell; cell dose ... See more keywords
Effects of CD34+ cell dose on haematopoietic recovery in acute lymphoblastic leukaemia patients with positive pretransplant measurable residual disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13974
Abstract: A higher CD34+ cell dose in allografts is associated with faster haematopoietic recovery after allogeneic haematopoietic stem cell transplantation (allo‐HSCT). Leukaemia stem cells impair normal bone marrow (BM) niches and induce BM failure during leukemogenesis.… read more here.
Keywords: cell; leukaemia; haematopoietic recovery; cd34 cell ... See more keywords
Abstract 15733: CD34 + Cell Therapy is Associated With Improved Right Ventricular Function in Heart Failure With Preserved Ejection Fraction
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.15733
Abstract: Introduction: Right ventricular (RV) dysfunction is an important predictor of adverse prognosis in patients with heart failure with preserved ejection fraction (HFpEF). Hypothesis: We sought to investigate the effects of transendocardial CD34 + cell therapy… read more here.
Keywords: right ventricular; cd34 cell; cell; group ... See more keywords