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   Articles with "cd36" as a keyword



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Transcription factor SOX2 contributes to nonalcoholic fatty liver disease development by regulating the expression of the fatty acid transporter CD36

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recommendations! Published in 2021 at "FEBS Letters"

DOI: 10.1002/1873-3468.14193

Abstract: Nonalcoholic fatty liver disease (NAFLD) can lead to hepatocellular carcinoma (HCC). The level of the transcription factor SOX2 correlates with HCC progression, but its role in fat accumulation remains unclear. Here, a high‐fat diet, with… read more here.

Keywords: fatty liver; cd36; transcription factor; sox2 ... See more keywords
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Genetic variants, gene expression, and soluble CD36 analysis in acute coronary syndrome: Differential protein concentration between ST‐segment elevation myocardial infarction and unstable angina

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recommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24529

Abstract: Atherosclerosis plays an important role in the pathophysiology of acute coronary syndrome (ACS). CD36 is a scavenger receptor involved in lipid metabolism. Some single‐nucleotide variants in the non‐coding region could indirectly alter the expression and… read more here.

Keywords: cd36; coronary syndrome; acute coronary; expression ... See more keywords
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CD36 Is a Marker of Human Adipocyte Progenitors with Pronounced Adipogenic and Triglyceride Accumulation Potential

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recommendations! Published in 2017 at "STEM CELLS"

DOI: 10.1002/stem.2635

Abstract: White adipose tissue (WAT) expands in part through adipogenesis, a process involving fat cell generation and fatty acid (FA) storage into triglycerides (TGs). Several findings suggest that inter‐individual and regional variations in adipogenesis are linked… read more here.

Keywords: pronounced adipogenic; human adipocyte; cd36; differentiation ... See more keywords
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Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.07.077

Abstract: Adipogenesis is a process of differentiation from preadipocyte into adipocyte, and is regulated by several transcription factors, including the peroxisome proliferator-activated receptor gamma (PPARγ) and the CCAAT-enhancer-binding protein alpha (C/EBPα). CD36 is a membrane protein… read more here.

Keywords: suppression cd36; attenuates adipogenesis; cd36 attenuates; cd36 ... See more keywords
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MicroRNA-26a-CD36 signaling pathway: Pivotal role in lipid accumulation in hepatocytes induced by PM2.5 liposoluble extracts.

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recommendations! Published in 2019 at "Environmental pollution"

DOI: 10.1016/j.envpol.2019.01.112

Abstract: Exposure to ambient particular matters (PM) has been associated with the development of non-alcoholic fatty liver disease (NAFLD), but the underlying mechanism remains unclear. Given that microRNA (miRNA) is recognized as a key regulator of… read more here.

Keywords: induced pm2; liposoluble extracts; lipid accumulation; pm2 liposoluble ... See more keywords
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Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance.

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recommendations! Published in 2018 at "Immunity"

DOI: 10.1016/j.immuni.2018.04.007

Abstract: The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medullary thymic epithelial cells… read more here.

Keywords: tolerance; allo; cd36; receptor ... See more keywords
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CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

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recommendations! Published in 2021 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2021.101428

Abstract: Objective Enhanced de novo lipogenesis (DNL) in hepatocytes is a major contributor to nonalcoholic fatty liver disease (NAFLD). Fatty acid translocase (FAT/CD36) is involved in the pathogenesis of NAFLD through facilitating free fatty acids uptake.… read more here.

Keywords: srebp1 processing; novo lipogenesis; cd36; cd36lko mice ... See more keywords
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CD36 in Alzheimer’s Disease: An Overview of Molecular Mechanisms and Therapeutic Targeting

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recommendations! Published in 2021 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2020.11.003

Abstract: CD36 is a membrane protein with wide distribution in the human body, is enriched in the monocyte-macrophage system and endothelial cells, and is involved in the cellular uptake of long chain fatty acids (LCFA) and… read more here.

Keywords: disease overview; alzheimer disease; cd36 alzheimer; cd36 ... See more keywords
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Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

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recommendations! Published in 2020 at "Redox Biology"

DOI: 10.1016/j.redox.2020.101591

Abstract: Macrophages play a pivotal role in the early stages of atherosclerosis development; they excessively accumulate cholesterol in the cytosol in response to modified Low Density Lipoprotein (mLDL). The mLDL are incorporated through scavenger receptors. CD36… read more here.

Keywords: reduces cholesterol; raw264 macrophages; nitro oleic; oleic acid ... See more keywords
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Generation of induced pluripotent stem cell line derived from FNAIT patient with CD36 deficiency mutations.

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recommendations! Published in 2022 at "Stem cell research"

DOI: 10.1016/j.scr.2022.102749

Abstract: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) caused by anti-CD36 isoantibodies is a common disease and the frequency of type I CD36 deficiency is relatively high in eastern Asian populations.Currently, patient-specific induced pluripotent stem cells (hiPSC)… read more here.

Keywords: cd36; cd36 deficiency; stem; pluripotent stem ... See more keywords
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Activation of AMPK by berberine induces hepatic lipid accumulation by upregulation of fatty acid translocase CD36 in mice

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recommendations! Published in 2017 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2016.12.019

Abstract: Abstract Emerging evidence has shown that berberine has a protective effect against metabolic syndrome such as obesity and type II diabetes mellitus by activating AMP‐activated protein kinase (AMPK). AMPK induces CD36 trafficking to the sarcolemma… read more here.

Keywords: lipid accumulation; activation ampk; fatty acid; cd36 ... See more keywords