CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD+-Sirt1-PGC1α signaling pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0454
Abstract: Obesity is a metabolic syndrome characterized by abnormal lipid deposition and energy imbalance. CD38 is a single chain transmembrane glycoprotein widely expressed in a variety of cell types. The roles of skeletal muscle and brown… read more here.
Keywords: pgc1; energy; cd38 deficiency; muscle brown ... See more keywords
CD38 Deficiency Protects Heart from High Fat Diet-Induced Oxidative Stress Via Activating Sirt3/FOXO3 Pathway
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DOI: 10.1159/000492651
Abstract: Background/Aims: Previous studies showed that CD38 deficiency protected heart from ischemia/reperfusion injury and high fat diet (HFD)-induced obesity in mice. However, the role of CD38 in HFD-induced heart injury remains unclear. In the present study,… read more here.
Keywords: cd38; heart; cd38 deficiency; oxidative stress ... See more keywords