CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging
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DOI: 10.1111/acel.13589
Abstract: Nicotinamide adenine dinucleotide (NAD) levels decline during aging, contributing to physical and metabolic dysfunction. The NADase CD38 plays a key role in age‐related NAD decline. Whether the inhibition of CD38 increases lifespan is not known.… read more here.
Keywords: inhibitor 78c; increases mice; cd38; cd38 inhibitor ... See more keywords