CD38 Knockout Primary NK Cells to Prevent "Fratricide" and Boost Daratumumab Activity
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DOI: 10.1182/blood-2019-129456
Abstract: Multiple myeloma (MM) is a plasma cell neoplasm typically characterized by high and uniform CD38 expression. Daratumumab (DARA), a humanized monoclonal antibody targeting CD38 has dramatically improved the outcome of patients with refractory MM, but… read more here.
Keywords: cd38ko cells; primary cells; dara; cd38 ... See more keywords