Articles with "cd3e immunotoxin" as a keyword



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CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1011190

Abstract: CD3-epsilon(CD3e) immunotoxins (IT), a promising precision reagent for various clinical conditions requiring effective depletion of T cells, often shows limited treatment efficacy for largely unknown reasons. Tissue-resident T cells that persist in peripheral tissues have… read more here.

Keywords: cd3e; cell; cd3e treatment; cd3e immunotoxin ... See more keywords