The impact of selenium on regulatory T cell frequency and immune checkpoint receptor expression in patients with diffuse large B cell lymphoma (DLBCL)
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-02889-5
Abstract: For many decades, selenium (Se) has been known as a potential anti-cancer agent that can also improve the function of immune cells in a variety of solid tumors. However, there is no report on the… read more here.
Keywords: cd4 cd25; frequency; expression; checkpoint ... See more keywords
Shikonin Controls the Differentiation of CD4+CD25+ Regulatory T Cells by Inhibiting AKT/mTOR Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Inflammation"
DOI: 10.1007/s10753-019-00982-7
Abstract: CD4+CD25+ regulatory T (Treg) cells maintain the function of immune tolerance and the balance of immune cells. Defects in the number and function of Treg cells can induce the development and progression of inflammatory disease.… read more here.
Keywords: treg cells; cells inhibiting; inhibiting akt; cd4 cd25 ... See more keywords
Analysis of FOXP3+ regulatory T cell subpopulations in peripheral blood and tissue of patients with systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2017 at "Immunologic Research"
DOI: 10.1007/s12026-017-8904-4
Abstract: Regulatory T cells (Tregs) are critical mediators of immune tolerance, yet their involvement in the autoimmune disease systemic lupus erythematosus (SLE) is incompletely understood. We analyzed CD4+ T cell subpopulations with Treg-related phenotypes and their… read more here.
Keywords: cd4 cd25; foxp3; cell subpopulations; cell ... See more keywords
Expansion of GARP-Expressing CD4+CD25-FoxP3+ T Cells and SATB1 Association with Activation and Coagulation in Immune Compromised HIV-1-Infected Individuals in South Africa.
Sign Up to like & getrecommendations! Published in 2021 at "Virologica Sinica"
DOI: 10.1007/s12250-021-00386-8
Abstract: Although antiretroviral treatment lowers the burden of human immunodeficiency virus (HIV)-related disease, it does not always result in immunological recovery. This manifests as persistent chronic inflammation, immune activation or exhaustion that can promote the onset… read more here.
Keywords: coagulation; cd4 cd25; hiv; cd25 ... See more keywords
The effect of maternal use of telbivudine on neonatal CD4+CD25+ regulatory T cells for the prevention of mother-to-child transmission of hepatitis B virus.
Sign Up to like & getrecommendations! Published in 2019 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2019.06.004
Abstract: Antiviral treatment could block mother-to-child transmission (MTCT) of hepatitis B virus (HBV) effectively. We examined whether maternal use of telbivudine (LdT) could decrease the proportion of CD4+CD25+ regulatory T cells and explored the immunological mechanism.… read more here.
Keywords: cd4 cd25; maternal use; mother child; child transmission ... See more keywords
Low expressions of PD-L1 and CTLA-4 by induced CD4+CD25+ Foxp3+ Tregs in patients with SLE and their correlation with the disease activity.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155119
Abstract: BACKGROUND The induction of CD4+CD25+Foxp3+ Treg from CD4+CD25- T cells is deficient in the patients with systemic lupus erythematosus (SLE). Whether the induced CD4+CD25+Foxp3+ Tregs possess defective function remains unclear. The purpose of the present… read more here.
Keywords: cd4 cd25; induced cd4; cd25; cd25 foxp3 ... See more keywords
Impairment of regulatory T cells in patients with neonatal necrotizing enterocolitis
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.07.029
Abstract: &NA; Necrotizing enterocolitis (NEC) is a life‐threatening condition that can occur in about 7% of pre‐term infants, and approximately 20% to 30% of the cases will end in death. An overactive immune response is thought… read more here.
Keywords: cd4 cd25; treg cells; non nec; nec infants ... See more keywords
Identification of tonsillar CD4+CD25-LAG3+ T cells as naturally occurring IL-10-producing regulatory T cells in human lymphoid tissue.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2016.09.005
Abstract: IL-10-producing regulatory T cells (IL-10-producing Tregs) are one of the regulatory T cell subsets characterized by the production of high amounts of IL-10, the lack of FOXP3 expression and the strong immunosuppressive capabilities. IL-10-producing Tregs… read more here.
Keywords: cd4 cd25; lag3; cd25 lag3; producing tregs ... See more keywords
Mesenchymal stromal cell exosome-enhanced regulatory T-cell production through an antigen-presenting cell-mediated pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2018.02.372
Abstract: BACKGROUND AIMS The immunomodulatory property of mesenchymal stromal cell (MSC) exosomes is well documented. On the basis of our previous report that MSC exosomes increased regulatory T-cell (Treg) production in mice with allogenic skin graft… read more here.
Keywords: mesenchymal stromal; production; cd4 cd25; cell ... See more keywords
Effect of adoptive transfer of CD4+CD25+Foxp3+ Treg induced by trichostatin A on the prevention of spontaneous abortion.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2018.12.002
Abstract: OBJECTIVE To investigate whether epigenetic modification of CD4+CD25- T-cells in vitro can make up for the inadequacy of CD4+CD25+Foxp3+ Treg in animal model of spontaneous abortion and prevent immune response-mediated spontaneous abortion. METHODS Trichostatin A… read more here.
Keywords: cd4 cd25; foxp3 treg; cd4; cd25 foxp3 ... See more keywords
Acceleratory effects of ambient fine particulate matter on the development and progression of atherosclerosis in apolipoprotein E knockout mice by down-regulating CD4+CD25+Foxp3+ regulatory T cells.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.09.005
Abstract: OBJECTIVE Atherosclerosis is an autoimmune inflammatory disease that is closely associated with long-term exposure to fine particulate matter (PM2.5). CD4+CD25+Foxp3+ regulatory T cells (Tregs) play a critical role in the regulation of T cell-mediated immune… read more here.
Keywords: cd4 cd25; pm2; atherosclerosis; cd25 foxp3 ... See more keywords