mTOR Inhibition Impairs the Activation and Function of Belatacept-Resistant CD4+CD57+ T Cells In Vivo and In Vitro
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DOI: 10.3390/pharmaceutics15041299
Abstract: Calcineurin inhibitors have improved graft survival in solid-organ transplantation but their use is limited by toxicity, requiring a switch to another immunosuppressor in some cases. Belatacept is one option that has been shown to improve… read more here.
Keywords: cd57 cells; mtor; belatacept resistant; cd4 cd57 ... See more keywords