Soluble CD40 ligand contributes to blood–brain barrier breakdown and central nervous system inflammation in multiple sclerosis and neuromyelitis optica spectrum disorder
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2017.01.024
Abstract: Soluble CD40 ligand (sCD40L) is reported to disrupt the blood-brain barrier (BBB). Cerebrospinal fluid (CSF) and serum sCD40L levels were measured in 29 multiple sclerosis (MS), 29 neuromyelitis optica spectrum disorder (NMOSD), and 27 disease… read more here.
Keywords: blood brain; soluble cd40; cd40 ligand; multiple sclerosis ... See more keywords
IL-17 and CD40 ligand synergistically stimulate the chronicity of diabetic nephropathy
Sign Up to like & getrecommendations! Published in 2018 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfw397
Abstract: Background Early stages of diabetic nephropathy (DN) are characterized by an influx of inflammatory cells. Interactions between infiltrating T cells and podocytes may play an important role in the ongoing inflammatory response and remodelling. The… read more here.
Keywords: cd4 cells; cd40 ligand; cd40; expression ... See more keywords
Relationship Between Plasma Levels of Soluble CD40 Ligand and the Presence and Severity of Isolated Coronary Artery Ectasia
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Applied Thrombosis/Hemostasis"
DOI: 10.1177/1076029616680476
Abstract: Objective: We aimed to investigate whether soluble CD40 ligand (CD40L) levels are higher in patients with isolated coronary artery ectasia (CAE) compared to patients with angiographically normal coronary arteries and those with stable coronary artery… read more here.
Keywords: cd40 ligand; soluble cd40; levels soluble; coronary artery ... See more keywords
The fruits of CD40 research in basic and clinical medicine will soon be harvested
Sign Up to like & getrecommendations! Published in 2023 at "Nagoya Journal of Medical Science"
DOI: 10.18999/nagjms.85.1.21
Abstract: . CD40/CD40 ligand interactions in immune responses and pulmonary immunity. Nagoya J Med Sci . 2011;73(3–4): 69–78. The CD40 ligand/CD40 pathway is widely recognized for its prominent role in immune regulation and homeostasis. CD40, a… read more here.
Keywords: fruits cd40; cd40 ligand; cd40; medicine ... See more keywords
The Proinflammatory Soluble CD40 Ligand Is Associated with the Systemic Extent of Stable Atherosclerosis
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DOI: 10.3390/medicina57010039
Abstract: Background and objectives: Polyvascular atherosclerosis is frequent and associated with a high cardiovascular risk, although the mechanisms regulating the atherosclerosis extent to single or multiple arterial territories are still poorly understood. Inflammation regulates atherogenesis and… read more here.
Keywords: soluble cd40; extent; scd40l levels; cd40 ligand ... See more keywords
Soluble CD40 ligand inhibits the growth of non-Hodgkin's lymphoma cells through the JNK signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Oncology Letters"
DOI: 10.3892/ol.2020.12318
Abstract: The incidence of non-Hodgkin's lymphoma (NHL) has been increasing annually and has become a serious threat to human health. However, the pathogenesis of NHL remains unclear. The present study aimed to investigate the effect of… read more here.
Keywords: lymphoma; hodgkin lymphoma; soluble cd40; cd40 ligand ... See more keywords