Addition of Anti-CD40 Monoclonal Antibody to Nonmyeloablative Conditioning With Belatacept Abrogated Allograft Tolerance Despite Induction of Mixed Chimerism
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DOI: 10.1097/tp.0000000000002417
Abstract: Background We recently reported anti-CD40 monoclonal antibody and rapamycin (aCD40/rapa) to be a reliable, nontoxic, immunosuppressive regimen for combined islet and kidney transplantation (CIKTx) in nonhuman primates. In the current study, we attempted to induce… read more here.
Keywords: allograft tolerance; monoclonal antibody; chimerism; mixed chimerism ... See more keywords