LINC00261/microRNA‐550a‐3p/SDPR axis affects the biological characteristics of breast cancer stem cells
Sign Up to like & getrecommendations! Published in 2020 at "IUBMB Life"
DOI: 10.1002/iub.2416
Abstract: Long non‐coding RNAs (lncRNAs) have been shown to play key roles in the pathogenesis of breast cancer (BC). The study was to explore the effect of long non‐coding RNA LINC00261/microRNA (miR)‐550a‐3p/serum deprivation response (SDPR) axis… read more here.
Keywords: 550a sdpr; mir 550a; cd44 cd24; bcscs ... See more keywords
Prognosis assessment of CD44+/CD24− in breast cancer patients: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-022-06402-w
Abstract: This meta-analysis investigated the relationships between the CD44+/CD24− phenotype and tumor size, lymph node metastasis, distant metastasis, disease-free survival (DFS), and overall survival (OS) in 8036 postoperative breast cancer patients enrolled in 23 studies. A… read more here.
Keywords: metastasis; cd44 cd24; breast cancer; cancer patients ... See more keywords
Metalloprotease-dependent activation of EGFR modulates CD44+/CD24− populations in triple negative breast cancer cells through the MEK/ERK pathway
Sign Up to like & getrecommendations! Published in 2017 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-017-4440-0
Abstract: PurposeThe CD44+/CD24− cell phenotype is enriched in triple negative breast cancers, is associated with tumor invasive properties, and serves as a cell surface marker profile of breast cancer stem-like cells. Activation of Epidermal Growth Factor… read more here.
Keywords: egfr; cd24 populations; cd44 cd24; activation ... See more keywords
Abstract 803: Targeting β-catenin/CBP signaling in OSCC
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-803
Abstract: Objectives: Oral squamous cell carcinoma (OSCC) is an aggressive malignancy characterized by molecular heterogeneity and locoregional spread associated with high morbidity. Aggressive cancers are thought to arise from populations of cancer initiating cells (CICs) that… read more here.
Keywords: targeting catenin; catenin cbp; catenin; cd44 cd24 ... See more keywords
Clinically relevant morphological structures in breast cancer represent transcriptionally distinct tumor cell populations with varied degrees of epithelial-mesenchymal transition and CD44+CD24- stemness.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18022
Abstract: Intratumor morphological heterogeneity in breast cancer is represented by different morphological structures (tubular, alveolar, solid, trabecular, and discrete) and contributes to poor prognosis; however, the mechanisms involved remain unclear. In this study, we performed 3D… read more here.
Keywords: morphological structures; cd44 cd24; breast cancer; epithelial mesenchymal ... See more keywords
CD44/CD24 and aldehyde dehydrogenase 1 in estrogen receptor-positive early breast cancer treated with tamoxifen: CD24 positivity is a poor prognosticator
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.23519
Abstract: CD44+/CD24- or aldehyde dehydrogenase 1 (ALDH1) has been suggested as a potential marker for breast cancer stem cells. In the cohort of 819 patients with resected ER-positive breast cancer, the ‘5-year relapse group’ within 5… read more here.
Keywords: positivity; cd44 cd24; breast cancer; relapse ... See more keywords
Reliability of CD44, CD24, and ALDH1A1 immunohistochemical staining: Pathologist assessment compared to quantitative image analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1040061
Abstract: Background The data on the expression of stem cell markers CD44, CD24, and ALDH1A1 in the breast tissue of cancer-free women is very limited and no previous studies have explored the agreement between pathologist and… read more here.
Keywords: assessment; image analysis; cd24 aldh1a1; cd44 cd24 ... See more keywords
A Systematic Review to Clarify the Prognostic Values of CD44 and CD44+CD24- Phenotype in Triple-Negative Breast Cancer Patients: Lessons Learned and The Road Ahead
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.689839
Abstract: As a unique population of tumor bulk, cancer stem cells have been implicated in tumor relapse and chemoresistance in triple-negative breast cancer (TNBC). Therefore, understanding the phenotype of cancer stem cells can pave the way… read more here.
Keywords: phenotype; tnbc patients; cd44 cd44; cd44 cd24 ... See more keywords
Association of human breast cancer CD44-/CD24- cells with delayed distant metastasis
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.65418
Abstract: Tumor metastasis remains the main cause of breast cancer-related deaths, especially delayed breast cancer distant metastasis. The current study assessed the frequency of CD44-/CD24- breast cancer cells in 576 tissue specimens for associations with clinicopathological… read more here.
Keywords: metastasis; breast cancer; cd44 cd24; cancer ... See more keywords