Expression of CD44 variant 9 induces chemoresistance of gastric cancer by controlling intracellular reactive oxygen spices accumulation
Sign Up to like & getrecommendations! Published in 2021 at "Gastric Cancer"
DOI: 10.1007/s10120-021-01194-5
Abstract: CD44 variant 9 (CD44v9) has been reported to suppress reactive oxygen spices (ROS) in association with antioxidant factors such as glutathione (GSH) and glutathione peroxidase 2 (GPx2), resulting in promoted tumor growth. CD44v9 and GPx2… read more here.
Keywords: chemotherapy; cd44v9 expression; gastric cancer; cd44v9 ... See more keywords
CD44 variant 9 expression as a predictor for gastric cancer recurrence: immunohistochemical and metabolomic analysis of surgically resected tissues.
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical research"
DOI: 10.2220/biomedres.38.41
Abstract: CD44 variant 9 (CD44v9) and the heavy chain of 4F2 cell-surface antigen (CD98hc) appear important for regulation of reactive oxygen species defence and tumor growth in gastric cancer. This study examined the roles of CD44v9… read more here.
Keywords: recurrence; gastric cancer; cd44v9; cd44 variant ... See more keywords
CD44v9 Induces Stem Cell-Like Phenotypes in Human Cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00417
Abstract: Background: Our previous study demonstrated an overexpression of CD44 variant 9 (CD44v9) in human cholangiocarcinoma (CCA) tissues that was associated with inflammation-related tumor development. However, the participation of CD44v9 in cholangiocarcinogenesis remains poorly understood. Therefore,… read more here.
Keywords: cca cells; human cholangiocarcinoma; cd44v9; expression levels ... See more keywords