Rapamycin treated tol-dendritic cells derived from BM-MSCs reversed graft rejection in a rat liver transplantation model by inducing CD8+CD45RC-Treg.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.03.018
Abstract: OBJECTIVE To investigate the influence of tolerance dendritic cells (tolDCs), generated from Bone marrow mesenchymal stem cells (BM-MSCs) treated with rapamycin (Rapa) on liver allograft survival in a rat acute liver transplantation model. METHODS Different… read more here.
Keywords: cd8; liver transplantation; transplantation; cd45rc ... See more keywords
Transient Anti-CD45RC mAb Treatment Induces Specific Transplant Tolerance Through Potentiation of Tregs
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation"
DOI: 10.1097/01.tp.0000520346.17326.53
Abstract: Introduction: The main goal in transplantation is to induce specific ra than general immunosuppression. The CD45 protein is an essential regu of T and B cell antigen receptor signaling. We have previously shown T cells… read more here.
Keywords: treatment; cd45rc mab; transplant tolerance; cd45rc ... See more keywords