LAUSR

CD46 accelerates macrophage‐mediated host susceptibility to meningococcal sepsis in a murine model

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0 Published in 2017 at "European Journal of Immunology"

DOI: 10.1002/eji.201646397

Abstract: CD46, a membrane cofactor expressed on all nucleated human cells, plays an essential role in suppressing autoimmune reactions and protecting host cells from complement‐mediated attack. Human transgenic CD46 homozygous mice (CD46+/+) are prone to lethal… read more here.

Keywords: sepsis; infection; cd46 accelerates; host ... See more keywords