CD47 Blockade and Cowpea Mosaic Virus Nanoparticle In Situ Vaccination Triggers Phagocytosis and Tumor Killing.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801288
Abstract: Contemporary immunotherapies, e.g., those that target the CTLA-4 and PD-1/PD-L1 axis, act on T cells to reinstate their antitumor activity. An alternative, and possibly more powerful approach is to target and reprogram the innate immune… read more here.
Keywords: cd47; blockade; cd47 blockade; situ vaccination ... See more keywords
SIRPĪ±-CD47 Blockade-Mediated Tumor Cell Phagocytosis Requires SLAMF7.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2017-081
Abstract: SLAMF7 expression is required for macrophage-mediated phagocytosis of hematopoietic tumor cells. read more here.
Keywords: mediated tumor; phagocytosis; blockade mediated; cd47 blockade ... See more keywords
Disulfiram/Copper Induces Immunogenic Cell Death and Enhances CD47 Blockade in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14194715
Abstract: Simple Summary The combination of disulfiram and copper is a novel anti-cancer drug under clinical development for the treatment of several tumor types including hepatocellular carcinoma. In this study, we investigated the potential of disulfiram… read more here.
Keywords: cell; hepatocellular carcinoma; disulfiram copper; copper ... See more keywords