TIGIT blockade repolarizes AML-associated TIGIT+ M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis
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DOI: 10.1136/jitc-2022-004794
Abstract: Background Leukemia-associated macrophages (LAMs) represent an important cell population within the tumor microenvironment, but little is known about the phenotype, function, and plasticity of these cells. The present study provides an extensive characterization of macrophages… read more here.
Keywords: cell; phagocytosis; leukemia; cd47 mediated ... See more keywords