Single-Cell Dissection Reveals Immune Dysregulation After CD5 or CD7-Directed Chimeric Antigen Receptor T-Cell Therapy.
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DOI: 10.1002/advs.202509259
Abstract: CD5- and CD7-directed chimeric antigen receptor T-cell (5CAR and 7CAR) therapies for T-cell malignancies carry the risk of life-threatening infection. Although depletion of target-positive lymphocytes is expected, the contribution of residual cell dysfunction to infection… read more here.
Keywords: cd7 directed; therapy; cd5 cd7; cell ... See more keywords