CD55 is upregulated by cAMP/PKA/AKT and modulates human decidualization via Src and ERK pathway and decidualization‐related genes
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23569
Abstract: Decidualization is an essential process for embryo implantation and maintenance of pregnancy, and abnormal decidualization contributed to several pregnancy disorders like a miscarriage. The objective of this study was to explore the regulation and function… read more here.
Keywords: cd55; expression; decidualization; decidualization related ... See more keywords
A structure-based approach for the development of a bicyclic peptide acting as a miniaturized anti-CD55 antibody.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.05.092
Abstract: CD55 is a major regulator of the complement system, a complex network of proteins that cooperate to clear tissue and blood pathogens from the organism. Indeed, overexpression of CD55 is associated with many diseases and… read more here.
Keywords: cd55; antibody; bicyclic peptide; complement ... See more keywords
Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2118590119
Abstract: Significance Receptor usage can affect cell tropism and viral pathogenicity. CVB causes viral-induced heart disease, aseptic meningitis, and many other severe diseases globally that can engage CAR in host cells and selectively utilizes CD55 to… read more here.
Keywords: cd55; receptor usage; receptor; differential receptor ... See more keywords
CD55 Facilitates Immune Evasion by Borrelia crocidurae, an Agent of Relapsing Fever
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01161-22
Abstract: Borrelia species are causative agents of Lyme disease and relapsing fever infections in humans. B. crocidurae causes one of the most prevalent relapsing fever infections in parts of West Africa. In the endemic regions, B.… read more here.
Keywords: crocidurae; cd55; relapsing fever; fever ... See more keywords
Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1058763
Abstract: End stage renal disease is an increasing problem worldwide driven by aging of the population and increased prevalence of metabolic disorders and cardiovascular disease. Currently, kidney transplantation is the only curative option, but donor organ… read more here.
Keywords: cell; complement; kidney; cd55 ... See more keywords
A novel therapeutic anti‑CD55 monoclonal antibody inhibits the proliferation and metastasis of colorectal cancer cells.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology reports"
DOI: 10.3892/or.2019.7337
Abstract: In recent years, efforts to treat cancer by improving the immune function of patients have received a great deal of attention. As part of the immune system, complement is also under such evaluation. Among the… read more here.
Keywords: cd55; colorectal cancer; cancer cells; cancer ... See more keywords