The aryl hydrocarbon receptor modulates the function of human CD56bright NK cells
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747289
Abstract: Human natural killer (NK) cells are divided into two subsets: CD56bright and CD56dim NK cells, which differ in maturation, function and distribution. Mechanisms regulating NK cell functions are not completely understood. Aryl hydrocarbon receptor (AhR)… read more here.
Keywords: cd56bright; hydrocarbon receptor; aryl hydrocarbon; function ... See more keywords
Interferon-γ production by tubulointerstitial human CD56bright natural killer cells contributes to renal fibrosis and chronic kidney disease progression.
Sign Up to like & getrecommendations! Published in 2017 at "Kidney international"
DOI: 10.1016/j.kint.2017.02.006
Abstract: Natural killer (NK) cells are a population of lymphoid cells that play a significant role in mediating innate immune responses. Studies in mice suggest a pathological role for NK cells in models of kidney disease.… read more here.
Keywords: chronic kidney; cd56bright cells; kidney disease; kidney ... See more keywords
Circulating CD56bright NK cells inversely correlate with survival of melanoma patients
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40933-8
Abstract: The roles of NK cells in human melanoma remain only partially understood. We characterized NK cells from peripheral blood ex vivo by flow cytometry obtained from late stage (III/IV) melanoma patients. Interestingly, we found that… read more here.
Keywords: melanoma; cells inversely; circulating cd56bright; melanoma patients ... See more keywords
Staphylococcus aureus β-Hemolysin Up-Regulates the Expression of IFN-γ by Human CD56bright NK Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.658141
Abstract: IFN-γ is produced upon stimulation with S. aureus and may play a detrimental role during infection. However, whether hemolysins play a role in the mechanism of IFN-γ production has not been fully characterized. In this… read more here.
Keywords: staphylococcus aureus; ifn production; ifn; cd56bright cells ... See more keywords