Single vesicle analysis of CD47 association with integrins and tetraspanins on extracellular vesicles released by T lymphoblast and prostate carcinoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12265
Abstract: Abstract CD47 regulates the trafficking of specific coding and noncoding RNAs into extracellular vesicles (EVs), and the RNA contents of CD47+ EVs differ from that of CD63+ EVs released by the same cells. Single particle… read more here.
Keywords: extracellular vesicles; cd63; evs; cd47 ... See more keywords
Gap-Plasmon Metasurface Combined with Bio-Barcode of CD63 Nanoflares for SERS Detection of Cancerous Exosomes.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c02115
Abstract: Exosomes (Exos) have garnered significant attention as promising noninvasive biomarkers for early cancer diagnosis due to their rich molecular information derived from parent cells. However, the sensitive and accurate detection of cancerous Exos remains challenging… read more here.
Keywords: bio barcode; cd63 nanoflares; cd63; detection cancerous ... See more keywords
Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-24384-2
Abstract: Despite their roles in intercellular communications, the different populations of extracellular vesicles (EVs) and their secretion mechanisms are not fully characterized: how and to what extent EVs form as intraluminal vesicles of endocytic compartments (exosomes),… read more here.
Keywords: small ectosome; secretion; versus small; specificities exosome ... See more keywords
The extracellular vesicle tetraspanin CD63 journey from the testis through the epididymis to mature bull sperm
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-81021-w
Abstract: The important role of extracellular vesicles, which are considered key mediators of intercellular communication under physiological and pathological conditions, in various cellular processes, including those crucial for mammalian reproduction, has been increasingly studied. Tetraspanins, including… read more here.
Keywords: extracellular vesicles; bull; cd63; testis epididymis ... See more keywords
An anion exchange membrane sensor detects EGFR and its activity state in plasma CD63 extracellular vesicles from patients with glioblastoma
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06385-1
Abstract: We present a quantitative sandwich immunoassay for CD63 Extracellular Vesicles (EVs) and a constituent surface cargo, EGFR and its activity state, that provides a sensitive, selective, fluorophore-free and rapid alternative to current EV-based diagnostic methods.… read more here.
Keywords: extracellular vesicles; egfr; cd63; membrane ... See more keywords
P109 The role and underlying mechanism of CD63+ erythroid progenitor cells in enhancing joint inflammation in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2025 at "Rheumatology"
DOI: 10.1093/rheumatology/keaf142.149
Abstract: Anemia is a prevalent hematologic complication in rheumatoid arthritis (RA), with its severity directly proportional to the degree of joint inflammation. However, the intricate relationship between anemia and RA progression remains elusive. Notably, CD63+ erythroid… read more here.
Keywords: joint inflammation; cd63 epcs; cd63; none ... See more keywords
Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies
Sign Up to like & getrecommendations! Published in 2024 at "Biology Open"
DOI: 10.1101/2024.02.15.580439
Abstract: Arf GTPase-Activating proteins (ArfGAPs) mediate the hydrolysis of GTP bound to ADP-ribosylation factors. ArfGAPs are critical for cargo sorting in the Golgi-to-ER traffic. However, the role of ArfGAPs in sorting into intralumenal vesicles (ILVs) in… read more here.
Keywords: mvbs; cd63; arap1 regulate; cd63 localization ... See more keywords
Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.01969-17
Abstract: ABSTRACT The tetraspanin protein CD63 has been recently described as a key factor in extracellular vesicle (EV) production and endosomal cargo sorting. In the context of Epstein-Barr virus (EBV) infection, CD63 is required for the… read more here.
Keywords: protein; epstein barr; secretion; lmp1 ... See more keywords
Molecular Mechanisms Underlying the Cellular Entry and Host Range Restriction of Lujo Virus
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.03060-21
Abstract: Lujo virus (LUJV) infects humans with high mortality rates, but the host range of LUJV remains unknown. We found that rodent-derived cell lines were less susceptible to LUJV infection than were human-derived cell lines, and… read more here.
Keywords: cell lines; host range; cd63; lujv ... See more keywords
Abstract 1349: Exploring CD63 as a targetable mediator of the pro-tumorigenic tissue microenvironment in HNSCC
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1349
Abstract: Introduction: Head and neck squamous cell carcinoma (HNSCC) is one of the ten most common cancer types worldwide - ranked on the sixth position with 560,000 new diagnoses and 270,000 deaths in 2020. The survival… read more here.
Keywords: cd63; expression; hnscc; exploring cd63 ... See more keywords
Salivary levels of azurocidin and soluble azurophilic granules in periodontal disease
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medicine and Life"
DOI: 10.25122/jml-2023-0286
Abstract: Periodontitis is an infection-driven inflammatory condition of the periodontium. Neutrophils are one of the most important first-line immune cells that protect against pathogen microorganisms in the saliva, but they may also mediate tissue death in… read more here.
Keywords: disease; cd63; levels azurocidin; azurophilic granules ... See more keywords