Prognostic significance of the infiltration of CD163+ macrophages combined with CD66b+ neutrophils in gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1420
Abstract: The polarization of tumor‐associated macrophages (TAMs) and tumor‐associated neutrophils (TANs), especially from the antitumoral phenotype to the protumoral phenotype under certain conditions, has an important influence on the progression of tumors. However, the interactions and… read more here.
Keywords: infiltration cd163; prognosis; infiltration; cd66b ... See more keywords
CD68+, but not stabilin-1+ tumor associated macrophages in gaps of ductal tumor structures negatively correlate with the lymphatic metastasis in human breast cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Immunobiology"
DOI: 10.1016/j.imbio.2015.09.011
Abstract: Tumor associated macrophages (TAM) support tumor growth and metastasis in several animal models of breast cancer, and TAM amount is predictive for efficient tumor growth and metastatic spread via blood circulation. However, limited information is… read more here.
Keywords: tumor; cd68 stabilin; tumor structures; breast cancer ... See more keywords
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post‐stroke
Sign Up to like & getrecommendations! Published in 2022 at "Brain Pathology"
DOI: 10.1111/bpa.13101
Abstract: With the hypothesis that perivascular microglia are involved as neuroinflammatory components of the gliovascular unit contributing to white matter hyperintensities on MRI and pathophysiology, we assessed their status in stroke survivors who develop dementia. Immunohistochemical… read more here.
Keywords: cd68 cells; cd68; perivascular microglial; dementia ... See more keywords
Antibody combinations for optimized staining of macrophages in human lung tumours
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12889
Abstract: The analysis of tumour‐associated macrophages (TAMs) has a high potential to predict cancer recurrence and response to immunotherapy. However, the heterogeneity of TAMs poses a challenge for quantitative and qualitative measurements. Here, we critically evaluated… read more here.
Keywords: cd206; lung tumours; macrophage; cd163 cd206 ... See more keywords
The hepatic effects in dams that ingested 2-aminoanthracene during gestation and lactation
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and Industrial Health"
DOI: 10.1177/0748233719875018
Abstract: Diabetes mellitus has been on a continual rise as one of the top chronic diseases to affect individuals worldwide. The goal of this study was to determine how exposure from a well-known toxicant, a polycyclic… read more here.
Keywords: hepatic effects; gestation; ingested aminoanthracene; effects dams ... See more keywords
The mechanisms of Ang II-induced hypertensive vascular remodeling under suppression of CD68 in macrophages.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201809_15948
Abstract: OBJECTIVE High blood pressure (hypertension) is one of the most common cardiovascular diseases. In recent years, there were more and more studies on the function of inflammation in hypertension. CD68 mainly mediates the activation of… read more here.
Keywords: ang induced; hypertensive vascular; induced hypertensive; vascular remodeling ... See more keywords
PD-1+CD8+ T Cells Proximal to PD-L1+CD68+ Macrophages Are Associated with Poor Prognosis in Pancreatic Ductal Adenocarcinoma Patients
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15051389
Abstract: Simple Summary The current methods for assessing tumor microenvironments (TMEs) using cellular markers and cell density-based assays do not identify the primitive phenotypes of single cells with multilineage selectivity or functional or cellular spatial information… read more here.
Keywords: cell; cd68; poor prognosis; cell density ... See more keywords
Higher Number of Tumor-Infiltrating PD-L1+ Cells Is Related to Better Response to Multikinase Inhibitors in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13081453
Abstract: Multikinase inhibitors (MKIs) such as sorafenib and lenvatinib are first-line treatments for unresectable hepatocellular carcinoma (HCC) and are known to have immunomodulatory effects. However, predictive biomarkers of MKI treatment in HCC patients need to be… read more here.
Keywords: hepatocellular carcinoma; hcc; cd68; multikinase inhibitors ... See more keywords
Intratumoral and peritumoral expression of CD68 and CD206 in hepatocellular carcinoma and their prognostic value
Sign Up to like & getrecommendations! Published in 2017 at "Oncology Reports"
DOI: 10.3892/or.2017.5738
Abstract: The aims of the present study were to determine whether the changes in density and location of CD68-positive and CD206-positive macrophages contribute to progression of hepatocellular carcinoma (HCC) and to evaluate prognostic values of these… read more here.
Keywords: cd68 cd206; cd206; hcc; cd68 positive ... See more keywords
Increased CD68/TGFβ Co-expressing Microglia/ Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Neurobiology"
DOI: 10.5607/en.2019.28.4.458
Abstract: The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in rhesus monkeys. We measured infarct… read more here.
Keywords: middle cerebral; transient middle; expressing microglia; microglia macrophages ... See more keywords