Changes of CD68, CD163, and PD-L1 tumor expression during high-dose-rate and pulsed-dose-rate brachytherapy for cervical cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Brachytherapy"
DOI: 10.1016/j.brachy.2019.09.009
Abstract: PURPOSE We hypothesized that radiation doses delivered with high-dose-rate (HDR) and pulsed-dose-rate (PDR) brachytherapy in patients with cervical cancer could trigger immune stimulation by modulating immune cells in the tumor microenvironment. The objective was to… read more here.
Keywords: cervical cancer; cd68 cd163; expression; brachytherapy ... See more keywords
Inflammatory cell infiltrates in advanced metastatic uveal melanoma.
Sign Up to like & getrecommendations! Published in 2017 at "Human pathology"
DOI: 10.1016/j.humpath.2017.06.005
Abstract: Current treatments for metastatic uveal melanoma (mUM) are limited and rarely prolong patient survival. Immunotherapy trials for mUM are few and to date have demonstrated only marginal success. High densities of tumor-associated macrophages (TAMs) and… read more here.
Keywords: within mum; cd68 cd163; density; uveal melanoma ... See more keywords
Prognostic significance of CD68+ and CD163+ tumor associated macrophages in head and neck squamous cell carcinoma: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2019.04.019
Abstract: OBJECTIVE Tumor associated macrophages (TAMs) are among the most abundant cells of the tumor microenvironment. Several studies have been performed to investigate whether TAM markers, namely CD68 and CD163, could serve as prognostic factors in… read more here.
Keywords: cd68 cd163; meta analysis; cd163; systematic review ... See more keywords
Myeloid-Derived Suppressor Cells and CD68+CD163+M2-Like Macrophages as Therapeutic Response Biomarkers Are Associated with Plasma Inflammatory Cytokines: A Preliminary Study for Non-Small Cell Lung Cancer Patients in Radiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/3621496
Abstract: Background Recent studies show that myeloid-derived suppressor cells (MDSCs) and M2-like macrophages are involved in the treatment of tumors; however, their therapeutic response role is rarely known in non-small cell lung cancer (NSCLC) during radiotherapy.… read more here.
Keywords: patients radiotherapy; cd163 like; nsclc patients; like macrophages ... See more keywords
High Infiltration of CD68+/CD163− Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Innate Immunity"
DOI: 10.1159/000524434
Abstract: Tumor-associated macrophages (TAMs) have emerged as key players in tumor immunology but demonstrate a continuum of functional states being either tumor suppressive or promoting. Moreover, chemotherapeutic agents have been shown to alter the tumor microenvironment.… read more here.
Keywords: cd68 cd163; chemotherapy; esophageal gastric; infiltration ... See more keywords
Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02925
Abstract: An array of phenotypically diverse myeloid cells and macrophages (MC&M) resides in the tumor microenvironment, requiring multiplexed detection systems for visualization. Here we report an automated, multiplexed staining approach, named PLEXODY, that consists of five… read more here.
Keywords: myeloid cells; cells macrophages; cd68 cd163; tissue ... See more keywords
Tumor-Associated CD68+, CD163+, and MARCO+ Macrophages as Prognostic Biomarkers in Patients With Treatment-Naïve Gastroesophageal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.534761
Abstract: Background: Despite improvements in surgical methodologies and perioperative chemo- and radiotherapy, the prognosis for patients with esophageal and gastric cancer remains poor. Hence, there is a great need to identify complementary biomarkers for improved treatment… read more here.
Keywords: gastroesophageal adenocarcinoma; cd163 marco; cd68 cd163; cd163 ... See more keywords
Low Infiltration of CD8+ PD-L1+ T Cells and M2 Macrophages Predicts Improved Clinical Outcomes After Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.658690
Abstract: Background Many clinical studies have shown that patients with non-small cell lung carcinoma (NSCLC) can benefit from immune checkpoint inhibitor (ICI) therapy; however, PD-L1 and tumor mutation burden (TMB), which are recommended by the NCCN… read more here.
Keywords: infiltration cd8; cd8 cells; cd8; cd68 cd163 ... See more keywords
Lung Expression of Macrophage Markers CD68 and CD163, Angiotensin Converting Enzyme 2 (ACE2), and Caspase-3 in COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Medicina"
DOI: 10.3390/medicina59040714
Abstract: Background and Objectives: The coronavirus (SARS-CoV-2) damages all systems and organs. Yet, to a greater extent, the lungs are particularly involved, due to the formation of diffuse exudative inflammation in the form of acute respiratory… read more here.
Keywords: pneumonia; expression; cd68 cd163; lung ... See more keywords