Articles with "cd71" as a keyword



Tracking Dye‐Independent Approach to Identify and Isolate In Vitro Expanded T Cells

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Published in 2019 at "Cytometry Part A"

DOI: 10.1002/cyto.a.23867

Abstract: T cell proliferation is routinely identified in vitro using tracking dyes or through detecting intracellular upregulation of the nuclear protein, Ki‐67. However, labeling with tracking dyes is cumbersome, associated with cellular toxicity, while Ki‐67 cannot… read more here.

Keywords: isolate vitro; tracking dye; cd71; identify isolate ... See more keywords
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Transferrin receptor 1 is a cellular receptor for human heme-albumin

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Published in 2020 at "Communications Biology"

DOI: 10.1038/s42003-020-01294-5

Abstract: Iron is essential for living cells. Uptake of iron-loaded transferrin by the transferrin receptor 1 (CD71, TFR) is a major but not sufficient mechanism and an alternative iron-loaded ligand for CD71 has been assumed. Here,… read more here.

Keywords: receptor; iron; heme albumin; cd71 ... See more keywords

Flow cytometric expression of CD71, CD81, CD44 and CD39 in B cell lymphoma

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Published in 2021 at "Scandinavian Journal of Clinical and Laboratory Investigation"

DOI: 10.1080/00365513.2021.1929446

Abstract: Abstract Flow cytometry is a useful ancillary tool for the diagnosis of nodal B cell lymphomas. Well-established antigens have diagnostic limitations. This study aimed to assess the expression of CD71, CD81, CD44 and CD39 by… read more here.

Keywords: cd81; cell lymphoma; cd71; expression ... See more keywords

Donor sex, pre‐donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates

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Published in 2023 at "Transfusion"

DOI: 10.1111/trf.17250

Abstract: Circulating CD71+ red blood cells (RBCs) have been reported to play an immunomodulatory role in vivo, which may contribute to adverse donor–recipient sex‐mismatched transfusion outcomes. However, it is not clear how CD71+ RBC quantity in… read more here.

Keywords: red cell; cd71; donor sex; cell concentrates ... See more keywords

INA03, a potent transferrin-competitive antibody-drug conjugate against CD71, for a safer acute leukemia treatment.

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Published in 2024 at "Molecular cancer therapeutics"

DOI: 10.1158/1535-7163.mct-23-0548

Abstract: Innovative strategies to enhance efficacy and overcome drug resistance in hematologic cancers such as antibody-drug conjugates (ADCs) have shifted the paradigm of conventional care by delivering promising outcomes in cancer therapies with a significant reduction… read more here.

Keywords: treatment; cd71; drug; antibody drug ... See more keywords

Abstract C074: Dual NR4A1/2 ligands inhibit rhabdomyosarcoma cell growth and trigger ferroptosis by activating CD71

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Published in 2025 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-25-c074

Abstract: Rhabdomyosarcoma (RMS) is the most prevalent soft tissue sarcoma in children and adolescents, with a poor prognosis in metastatic or treatment-resistant cases. Conventional therapies often fail to eliminate aggressive tumor populations. Ferroptosis, a regulated form… read more here.

Keywords: cd71; rhabdomyosarcoma; cell; ferroptosis ... See more keywords

CD71-Mediated Effects of Soluble Vasorin on Tumor Progression, Angiogenesis and Immunosuppression

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Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26104913

Abstract: Increasing recognition of the importance of the tumor microenvironment (TME) in cancer therapeutic strategies has led to more efforts to target molecules in the TME. Vasorin (VASN) is a transmembrane glycoprotein that can be cleaved… read more here.

Keywords: tumor progression; cd71; svasn; progression ... See more keywords